Role of Cytopathology in the Diagnosis of Benign Pulmonary Tumours
Dr Sampurna Roy MD November 2015
In some cases cytopathology has a role in the diagnosis of benign tumours of the respiratory tract.
- Chondroid Hamartoma : It presents as a coin lesion to be distinguished from primary malignancy or a metastasis.
FNA sampling shows a combination of myxoid material, benign epithelial cell fragments and a few adipose tissue cells.
Cartilage is occasionally obtained.
The myxoid material stains bright magenta on Giemsa staining but is inconspicuous in Papanicolaou stained preparations. Case Link
- Myofibroblastoma (Inflammatory pseudotumor, plasma cell granuloma) : There is a mixture of plasma cells, foamy macrophages, spindle shaped fibroblasts and inflammatory cells. There are no specific features but combining the findings with the clinical details of a lesion developing usually in a young patient following a "respiratory infection" may suggest the diagnosis. The lesion is now regarded as neoplastic in the light of cytogenetic studies. Visit: Pathology of Myofibroblastic tumours
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