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Role of Cytopathology in the Diagnosis  of Benign Pulmonary Tumours  

Dr Sampurna Roy MD                                    November 2015 


In some cases cytopathology has a role in the diagnosis of benign tumours of the respiratory tract.

Example:

 - Chondroid Hamartoma :  It presents as a coin lesion to be distinguished from primary malignancy or a metastasis.

FNA sampling shows a combination of myxoid material, benign epithelial cell fragments and a few adipose tissue cells.

Cartilage is occasionally obtained.

The myxoid material stains bright magenta on Giemsa staining but is inconspicuous in Papanicolaou stained preparations.  Case Link

-  Myofibroblastoma (Inflammatory pseudotumor, plasma cell granuloma) : There is a mixture of plasma cells, foamy macrophages, spindle shaped fibroblasts and inflammatory cells. There are no specific features but combining the findings with the clinical details of a lesion developing usually in a young patient following a "respiratory infection" may suggest the diagnosis. The lesion is now regarded as neoplastic in the light of cytogenetic studies. Visit: Pathology of Myofibroblastic tumours

                                                                                    

Further reading:

Cytologic features of pulmonary hamartoma. Report of a case diagnosed by fine needle aspiration cytology.

Fine needle aspiration biopsy of pulmonary hamartomas. Radiologic, cytologic and immunocytochemical study of 15 cases.

Pulmonary hamartoma: diagnosis by transthoracic needle-aspiration biopsy.

Pulmonary hamartomas: cytologic appearances of fine needle aspiration biopsy.

Inflammatory pseudotumor: a diagnostic dilemma in cytopathology.

Pulmonary inflammatory pseudotumor. Its diagnosis by fine-needle aspiration puncture

Fine-needle cytology of inflammatory myofibroblastic tumor of the lung. Report of a case.

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Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)

 

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