Cardiac Path Online

Pathology of Cardiac Teratoma

Dr Sampurna Roy MD





Cardiac teratoma is a benign germ cell neoplasm. Intra-pericardial teratoma is a life-threatening lesion. Excision brings immediate relief of symptoms.


Reporting of Cardiac Tumours

Age: The tumour typically affects infants and children.

Site: Teratomas are usually, intrapericardial tumours attached to the root of the aorta and pulmonary trunk, but may appear as intracardiac mass.

Pericardial teratomas are usually right-sided masses.

Rarely, the tumour can be intramyocardial.      

Pericardial Disease

Clinical presentation:  Cardiac enlargement is the dominant feature, often accompanied by signs and symptoms of cardiac compression.

The tumours may grow rapidly to a large size involving the entire mediastinum.

Gross: The tumours can be very large and are almost  always associated with a pericardial effusion.

Cut sections of these tumors are usually multicystic.

Microscopic features: Case of Cardiac Teratoma

Cardiac teratomas display features similar to benign extrapericardial teratomas.

The tumour contain derivatives of all three germ layers, with mature endodermal, mesodermal, and ectodermal elements.

Neuroglia, cartilage, skeletal muscle, liver, intestine, pancreas, and glandular tissue are often identified in the tumour.


Further reading:

Fetal pericardial teratoma: presentation of two cases and review of literature.

Fetal and neonatal cardiac tumors.

Perinatal (fetal and neonatal) germ cell tumors

Immature intrapericardial teratoma in a newborn with elevated alpha-fetoprotein.

Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation.





Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)









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