Custom Search

          

Dermpath-India

Pathology of Cutaneous Ciliated Cyst

Dr Sampurna Roy MD          

 

Dermatopathology Quiz Case 105

Diagnosis: Cutaneous Ciliated Cyst

 

                                                                                                                      

 

 

Cutaneous ciliated cyst is an exceedingly rare, benign lesion.

These are most commonly found in the dermis or subcutis of the lower extremities of young female patients in their second and third decades.

The cysts are usually less than 3 cm in diameter.

These cysts are lined by ciliated cuboidal to columnar epithelium with pseudostratified areas.

The pathogenesis of the cyst is unknown.

The histologic, immunohistochemical, and ultrastructural findings of some cases and the literature provide evidence in favour of the Mullerian heterotopia theory.  

  

 Microscopic images of Case 105

   

Immunostaining, staining reveals that the epithelial cells are positive for cytokeratin , estrogen receptor (ER) and progesterone receptor (PR).

Evidence in favour of Mullerian origin include the strong association with  the female gender, location on lower limbs, frequent growth during reproductive years, and the Estrogen Receptor (ER) and Progesterone Receptor (PR) positivity.

The differential diagnosis of cutaneous ciliated cyst includes other cutaneous cysts capable of showing cilia, namely, bronchogenic cyst, branchial cleft cyst, thymic cyst, thyroglossal duct cyst, vulvar cyst, perianal (caudal gut) cyst, and cutaneous endosalpingiosis.

 

Further reading

PAX-8 Expression in Cutaneous Ciliated Cysts: Evidence for Müllerian Origin.

Cutaneous ciliated cyst in the subcutaneous area.

Cutaneous ciliated cyst: a case report with focus on mullerian heterotopia and comparison with eccrine sweat glands.

Cutaneous ciliated cyst of the inguinal area in a man.

Cutaneous ciliated cyst of the abdominal wall: a case report with a review of the literature and discussion of pathogenesis.Am J Dermatopathol. 2002 Feb;24(1):63-6.

Cutaneous ciliated cyst: a case report with immunohistochemical evidence for dynein in ciliated cells.

Cutaneous ciliated cyst of the scalp. A case report with immunohistochemical evidence for estrogen and progesterone receptors.

 

 

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)


 

 

Histopathology-India.net

 

Pathopedia-India.com

 

Surgical Pathology.com

 

Pathology-India.com

 

Dermpath-India

 

Infectious Disease Online

 

Pathology Quiz Online 

 

Paediatric Pathology Online

 

Pancreatic Pathology Online

 

Paraganglioma-Online

 

Endocrine Pathology Online

 

Eye Pathology Online

 

Ear Pathology Online

 

Cardiac Path Online

 

Pulmonary Pathology Online

 

Lung Tumour Online

 

Mesothelioma-Online

 

Nutritional Pathology Online

 

Environmental Pathology Online

 

Soft Tissue Tumour Online

 

GI Path Online-India

 

Gallbladder Pathology Online

 

E-book - History of Medicine  

 

Microscope - Seeing the Unseen

 

 roypath.in

 

 

Disclaimer

Privacy Policy  

Advertising Policy

Copyright © 2017  histopathology-india.net