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Dermpath-India Pathology of Cutaneous Ciliated Cyst Dr Sampurna Roy MD 2022
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Cutaneous ciliated cyst is an exceedingly rare, benign lesion.
These are most commonly found in the dermis or subcutis of the lower extremities of young female patients in their second and third decades. The cysts are usually less than 3 cm in diameter. These cysts are lined by ciliated cuboidal to columnar epithelium with pseudostratified areas. The pathogenesis of the cyst is unknown. The histologic, immunohistochemical, and ultrastructural findings of some cases and the literature provide evidence in favour of the Mullerian heterotopia theory. Evidence in favour of Mullerian origin include the strong association with the female gender, location on lower limbs, frequent growth during reproductive years, and the Estrogen Receptor (ER) and Progesterone Receptor (PR) positivity. The differential diagnosis of cutaneous ciliated cyst includes other cutaneous cysts capable of showing cilia, namely, bronchogenic cyst, branchial cleft cyst, thymic cyst, thyroglossal duct cyst, vulvar cyst, perianal (caudal gut) cyst, and cutaneous endosalpingiosis.
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