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February
2009
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Pulmonary Pathology Online Non- Neoplastic Pulmonary Diseases Anatomy and Histology of the Normal Lung and Airways Examination of pulmonary and pleural biopsies Useful chromatic and immunostains in pulmonary pathology Percutaneous Needle and Trucut Biopsy Specimen Transbronchial Biopsy Specimen Transbronchial biopsy in lung transplant recipients Lobectomy and pneumonectomy specimen Histopathological reporting of pulmonary parenchymal biopsies Histopathological reporting of pulmonary biopsies in cases of Idiopathic Pulmonary Fibrosis Closed pleural biopsy for neoplasm or inflammatory lesions ; Open pleural biopsy and pneumonectomy or pleural stripping Anatomical Distribution of Pulmonary Disease Congenital Cystic Adenomatoid Malformation Bronchopulmonary Sequestration Acute Respiratory Distress Syndrome Neonatal Respiratory Distress Syndrome Complications of Neonatal Respiratory Distress Syndrome Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis) Pulmonary Eosinophilic Granuloma Chronic Obstructive Pulmonary Disease Emphysema Bronchiolitis |
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Ectopic hamartomatous thymoma (EHT) is a rare benign neoplasm which was was named by Rosai et al. in 1984.Ectopic hamartomatous thymoma. A distinctive benign lesion of lower neck.Am J Surg Pathol. 1984 Jul;8(7):501-13. It arises from misplaced branchial pouch derivatives (which normally forms thymic tissue). Some studies suggest its origin from salivary gland. Pitfalls in the diagnosis of ectopic hamartomatous thymoma.Histopathology. 1996 Dec;29(6):549-55. According to recent studies it has been suggested that the tumour should be reclassified as a 'branchial anlage mixed tumor 'Ectopic hamartomatous thymoma: a clinicopathologic and immuno histochemical analysis of 21 cases with data supporting reclassification as a branchial anlage mixed tumor.Am J Surg Pathol. 2004 Oct;28(10):1360-70. Clinical presentation: The tumour arises in adults, mostly male, as a slowly growing, sub-fascial swelling in the supra-sternal or supra-clavicular region. The tumour usually does not recur. Gross: A well circumscribed swelling measuring 5 cm or less. Microscopic features: Consists of variable proportions of : i) Bland spindle cells with pale cytoplasm & tapering nuclei, arranged in fascicles. ii) Island of mature adipose tissue iii) Epithelial components are arranged in tubules or glands with epithelium that varies from non-keratinizing squamous, cuboidal or glandular elements. Character of the cells are benign and mitosis is rare. Immunohistochemistry: Strong & diffuse positivity for cytokeratin and epithelial membrane antigen (EMA) in the spindle cell areas suggested thymic nature. According to recent studies immunohistochemical analysis of the tumour revealed a complex immunophenotype with a diverse keratin profile. The plump spindled cells revealed a myoepithelial phenotype, as evidenced by the coexpression of cytokeratins , alpha-smooth muscle actin and CD10. The tumour is negative for S-100 protein, glial fibrillary acidic protein, and CD34. Differential diagnosis: The differential diagnosis includes mixed tumours of skin adnexal or salivary gland origin, synovial sarcoma, glandular malignant peripheral nerve sheath tumor and cystic teratoma. Visit: Myxoid Tumours of Soft Tissue ; Soft Tissue Tumours of Uncertain Differentiation ; Neural tumours ; Vascular tumours ; Fibroblastic/Myofibroblastic tumours ; Myofibroblastic tumours ; Myogenic tumours ; ChondroOsseous tumours
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ENDOMYOCARDIAL BIOPSY-(ALLOGRAFT REJECTION): ISHLT SYSTEM FOR GRADING REJECTION POST-OPERATIVE CARDIAC PATHOLOGY PERIOPERATIVE CARDIAC PATHOLOGY MESOTHELIOMA OF ATRIOVENTRICULAR NODE |
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Pulmonary Alveolar Proteinosis Other forms of Pulmonary Embolism Pulmonary EdemaPathological Diagnosis of Granulomatous Lung Diseases Infectious Granuloma of the Lung Non-necrotising Granulomatous Inflammation of the lung Pneumoconiosis |
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Mesothelioma -Online Aetiology and Pathogenesis of Mesothelioma Gross features of Mesothelioma Microscopic features of Mesothelioma Cytological Diagnosis of Mesothelioma Histochemistry and Immunohistochemistry in the diagnosis of Mesothelioma |