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Pathology of Eosinophilic


Dr Sampurna Roy MD

GI Path Online- Home Page Gastric Pathology - Home Page

August  2015


Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)


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Autoimmune Gastritis (Type A) 

Reactive /Reflux/ Chemical Gastritis (Type C)

Lymphocytic Gastritis

Collagenous Gastritis

Granulomatous Gastritis

Eosinophilic Gastritis

Gastric Xanthoma/ Xanthelasma

Other Non-Neoplastic Gastric Lesions

Benign tumour and tumour-like lesions

Gastric Lymphoma

Gastric Carcinoid Tumour

- Eosinophilic gastroenteritis

- Parasite reactions 

- Allergic gastritis

- Drug reaction

- Foreign bodies

- Peptic ulcer

- Associated with inflammatory fibroid polyp, adenoma, carcinoma  and T- cell lymphoma. 


Features of Eosinophilic Gastroenteritis:

Visit: Eosinophilic Gastroenteritis

Visit: Pathology Quiz Case 60

- Patient presents with abdominal pain.

- Peripheral blood eosinophilia.

- IgE increased in blood.

- Eosinophilic infiltration of mucosa,  submucosa, muscularis propria or the serosa.

- Mucosal edema, vascular dilatation.

- 10 - 50 eosinophils / high power field

- Displaces and destroys gastric pits and glands.


Further reading:

Histologic eosinophilic gastritis is a systemic disorder associated with blood and extragastric eosinophilia, TH2 immunity, and a unique gastric transcriptome.

Eosinophilic gastritis with gastric outlet obstruction mimicking infantile hypertrophic pyloric stenosis.

Rare association of IgA nephropathy with nephrotic syndrome in a patient with eosinophilic gastritis.

Eosinophilic gastritis in children: clinicopathological correlation, disease course, and response to therapy.

A childhood case of eosinophilic gastritis and protein-losing enteropathy.

Gastric pneumatosis with associated eosinophilic gastritis in four black and white ruffed lemurs (Varecia variegata variegata).

Snakeskin-like pattern mimicking portal hypertensive gastropathy in patient with eosinophilic gastritis.

Eosinophilic gastritis: histopathological characterization and quantification of the normal gastric eosinophil content.


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Normal Histology of Esophagus

An approach to the reporting of esophageal biopsies

Benign tumours and tumour -like conditions of esophagus.

 1. Squamous papilloma of the esophagus

 2.Inflammatory fibroid polyp of the esophagus

 3. Leiomyoma of the esophagus

 4. Granular cell tumour of the esophagus

 5. Esophageal cysts 

 6. Glycogenic acanthosis 

Reporting of esophageal resection specimens

Squamous epithelial dysplasia  including squamous cell carcinoma in-situ of the esophagus

Small cell carcinoma of the esophagus 

Drug related lesions of the gastrointestinal tract.


An outline of the anatomy and normal histology of the  stomach for pathologists.

Reporting of gastric biopsies (non-neoplastic gastric lesions).

Pathology and pathogenesis of peptic ulcer.

Acute Gastritis 

Chronic Gastritis Helicobacter pylori  associated (TypeB)  Gastritis 

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