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 Soft Tissue Pathology Online

Pathology of Fibrohistiocytic Tumours

Dr Sampurna Roy MD





Fibrous Histiocytoma (Dermatofibroma)


Epithelioid Fibrous Histiocytoma


Plexiform Fibrohistiocytic Tumour


Giant Cell Fibroblastoma  


Dermatofibrosarcoma Protuberans  


Atypical Fibroxanthoma  


Pleomorphic Sarcoma (Malignant Fibrous Histiocytoma) 


Further reading:

Fibrohistiocytic tumors of the skin: a heterogeneous group of superficially located mesenchymal neoplasms.

" So-called fibrohistiocytic tumors of the skin comprise a heterogeneous spectrum of superficially located neoplasms that often show fibroblastic and/or myofibroblastic differentiation. In this review clinicopathologically important variants of dermatofibroma and dermatofibrosarcoma protuberans and their differential diagnoses are discussed in detail. In addition, the clinicopathological features of atypical fibroxanthoma, angiomatoid fibrous histiocytoma, plexiform fibrohistiocytic tumors and pleomorphic dermal sarcoma are presented. Entities that have to be considered in the differential diagnosis are also mentioned."

Immunohistochemical evaluation of p16 expression in cutaneous histiocytic, fibrohistiocytic, and undifferentiated lesions.

Cutaneous and subcutaneous fibrohistiocytic tumors of intermediate malignancy: an update.

Fibrohistiocytic skin lesions.







Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)






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