Folliculitis

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Dr Sampurna Roy MD

http://www.histopathology-india.net/dermpath.htm

May 2007

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Normal Histology of Skin

Glossary

Gross examination of the skin specimen

Reporting of biopsies taken for Inflammatory Skin Diseases

Lichenoid (Interface)Tissue Reaction Pattern

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Histopathological patterns in cutaneous infections

1: Bacterial, Rickettsial and Chlamydial infection

2 : Spirochetal Infection

3 : Mycoses and algal infections

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5 : Helminth Infections

6 : Viral Infections

Cutaneous lesion associated
with AIDS

Folliculitis is an inflammatory process distributed around hair follicles and involving follicular opening or adjacent perifollicular skin. Patients with depressed immune system, diabetes mellitus and obesity have a greater risk of contracting folliculitis.

Common sites for folliculitis are scalp, face, thigh, legs and buttock.

CLASSIFICATION:

I Infectious-
Superficial- (usually suppurative)- Bacteria, fungus, syphilis, virus

Deep- (usually granulomatous)- Fungi or bacteria

II Non infectious-
Superficial- (usually suppurative)- Acne vulgaris, rosacea, follicular mucinosis, steroid induced.

Deep- (usually granulomatous)- Acne vulgaris- conglobata & keloidal forms and perforating form.

Deep- (scarring) folliculitides- Folliculitis decalvans ; Folliculitis keloidalis nuchae.

Spongiotic- Fox fordyce disease, atopic dermatitis, pruritic folliculitis of pregnancy.

III Perifolliculitis-
Predominantly lymphocytic- Lichen planopilaris, pityriasis rubra pilaris.

Predominantly granulomatous- Rosacea, dermatitis perioralis.

INFECTIOUS FOLLICULITIS

Visit: Histopathological patterns in cutaneous infection
The most common cause of folliculitis is infection by bacteria, staphylococcus aureus.
Other infective folliculitis include Pseudomonas folliculitis (hot-tub folliculitis). This is characterised by dense collection of polymorphs in pilar canal and prominent perifollicular lymphocytic infiltration.
Gram (-) folliculitis caused by Klebsiella or Enterobacter (usually around nose), Pityrosporum folliculitis,tinea capitis and tinea barbae causing folliculitis (fungal infection caused by candidial species and dermatophytes).
Eosinophilic pustular folliculitis is usually seen in HIV
positive patients.
Herpetic folliculitis caused by Herpes simplex virus may produce vesicles and pustules in the beard area of men.

IMAGE LINK(Dr.Weems)

ACNE ROSACEA

Affects mainly center and sides of the face
Grade I- Erythematous telangiectatic
Grade II-. Papular /papulopustular
Grade III- Nodular/plaque

There is sebaceous hyperplasia & periadnexal inflammation. In some cases granulomatous infiltrate is present. Intact or fragmented Demodex is sometimes present.

                               ACNE VULGARIS

Occurs mostly during adolescence .Usual sites are face and upper half of trunk.

The lesion presents as :
Grade I   Comedones-
Black heads (open follicles)
White heads (closed follicles)

Grade II Papulopustules
Grade III Nodulocystic (conglobata)

The ruptured pilosebaceous unit is surrounded by neutrophils. There is foreign body (granulomatous) reaction to the follicular contents. If collection of polymorphs is small and superficial a pustule results.
If the collection is large and deep a nodule forms.