Images of clear cell hidradenoma
Path Quiz Case- 75
Diagnosis: Poroid Hidradenoma
Path Quiz Case- 77
Diagnosis: Clear Cell Hidradenoma
Dr Sampurna Roy
MD
Images of poroid hidradenoma
|
|
Benign sweat gland tumours Cysts: Hydrocystoma -Eccrine/Apocrine Porokeratotic eccrine ostial naevus Benign Neoplasms: Syringocystadenoma Papilliferum Chondroid Syringoma (benign mixed tumour) Low grade: Primary extramammary Paget’s disease Intermediate grade: Digital papillary adenocarcinoma High grade: |
| Sebaceous tumours |
| Pathology of the Eyelid Inflammatory diseases of the Eyelid Tumour and tumour-like lesions of the Eyelid Epidermal tumours of the Eyelid |
|
Syn: Clear cell hidradenoma, solid and cystic hidradenoma or dermal acrospiromas. Hidradenoma is a benign dermal appendage tumour. Hidradenomas may be of eccrine or apocrine origin. Solitary, nodule often partly solid, partly cystic. Site: Located in any part of the body. There is a slight predilection for the head, face, and upper extremities. Microscopic features: Well-circumscribed dermal tumor with a grenz zone between the tumour and the epidermis ; Variously shaped tumour islands in the dermis ; May extend into the subcutis ; Combination of solid and cystic areas ; Cystic spaces form as a result of tumour cell degeneration ; The intervening stroma varies from delicate vascularized fibrous tissue to dense hyalinized collagen ; Minimal epidermal connection may be present ; Foci of squamous differentiation; Ductal differentiation and intracytoplasmic lumina ; Mitotic figures are often present which is of little prognostic significance. Two types of cells - One cell type is polyhedral with a rounded nucleus and slightly basophilic cytoplasm. The second cell type is generally round with clear cytoplasm. Variants: Clear cell ; Poroid ; Oncocytic ; Epidermoid, and Pigmented. Images of Clear cell Hidradenoma : Image1 ; Image2 ; Image3 ; Image4 ; Image5. Images of Poroid Hidradenoma: Image1 ; Image2 ; Image3 ; Image4. Clear cell hidradenomas are characterized by prominent clear cells which is present in less than one third of hidradenomas. Mucus producing cells are found in some cases. The clear cells contain glycogen and periodic acid-Schiff-positive, diastase-resistant material, but no lipid.(Dr Weems): Image1 ; Image2 Poroid hidradenomas are well circumscribed , non-encapsulated tumours composed of predominantly poroid cells. Cytologically this variant resembles an eccrine poroma. Atypical hidradenomas- cytological atypia or infiltrative margins; higher rate of recurrence and malignancy. The significance of atypical nuclear changes in benign eccrine acrospiromas: a clinical and pathological study of 18 cases.J Cutan Pathol. 1984 Feb;11(1):35-44. Nodular hidradenoma can recur after inadequate excision. Differential diagnosis: It is sometimes difficult to distinguish solid cellular hidradenomas without duct-like structures and glomus tumour without a vascular pattern. Clear cell hidradenoma: D/D- Clear cell tumours of skin ; Hidradenocarcinoma: click here . (Clear cell hidradenoma: a mimic of metastatic clear cell tumors. Arch Pathol Lab Med. 2005;129(5):e 113-6.) |
|
Histopathology-India.net diagnostichistopathology. blogspot.com Environmental Pathology Online
E-book - History of Medicine with special reference to India. |
|
Tumours of the Hair Follicle Hair Germ Differentiation: Desmoplastic Trichoepithelioma
Cutaneous lymphadenoma Tumour of Follicular Infundibulum Outer root
sheath differentiation: Proliferating Trichilemmal Cyst (Pilar Tumour)
Matrical differentiation: |
Interstitial Granulomatous Drug Reaction
|
Granulomatous Reaction Pattern of the Skin
AnnularElastolytic Giant Cell Granuloma |