|
Old
term |
Grades |
Notes |
Proposed
simplification (1994) |
|
No rejection |
0 |
Biopsies with very sparse lymphoid infiltrates
should be included in this grade. |
|
|
Mild rejection |
1A |
Focal perivascular or interstitial infiltrates.
The mild intensity and lack of myocyte damage distinguish this from
higher grades. |
Grade 1 |
|
Mild rejection |
1B
|
Diffuse
but sparse infiltrate. As with 1A, there must be no myocyte damage. |
Grade 1 |
|
‘Focal’ moderate rejection |
2 |
One focus only with aggressive infiltration and/or
focal myocyte damage. The choice of a single focus as the cut-off from
higher grades is arbitrary in practice, with the amount of tissue
usually submitted, one is unlikely to be faced with the problem of
biopsy fragments with only two foci |
Grade 1 |
