DermPath-India

     Site created by

 Dr Sampurna Roy MD

          

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                                       HISTOPATHOLOGY INDIA.COM

    Myxoid Tumours of Soft Tissue

        Dr  Sampurna Roy  MD

 
   Gastrointestinal Stromal Tumour

     

http://www.histopathology-india.net/SoftTissuePath.htm

February  2009 
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Normal Histology of Skin

Glossary 

Gross examination of the skin specimen

Reporting of biopsies taken for Inflammatory Skin Diseases

Psoriasiform Reaction Pattern

Vesiculobullous Reaction Pattern

Spongiform Reaction Pattern

Vasculopathic Reaction Pattern

Lichen planus-like lesions

Bullous Pemphigoid

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Hailey-Hailey Disease

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Folliculitis

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Drug related cutaneous lesions

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Cutaneous Pseudolymphoma

Cutaneous infection and infestations

Histopathological patterns in cutaneous infections

                  
Interface dermatosis is a common form of inflammatory dermatosis. A wide range of inflammatory skin diseases exhibit interface change with considerable overlap of histological features.
The term "lichenoid" is avoided by some pathologists because of clinical and histological difference in the definition of this term.

The following features are characteristic of interface dermatitis:

I-  Mild or dense inflammatory infiltrate composed of mainly mononuclear cells. This feature is essential to make a diagnosis of an interface dermatitis.
II-  Vacuolar or hydropic change due to basal cell degeneration.
III- Colloid or civatte bodies are eosinophilic bodies formed as a result of apoptosis. These may be present in the lower part of the epidermis (suprabasal) or in the dermis.
IV-  Pigment incontinence due to damage of basal keratinocytes and melanocytes.

                       

Interface dermatitis is divided into five groups-

I- Lichenoid (lichen planus-like) interface reactions:  click

       Eg-    Lichen Planus     
                Lichenoid keratosis
                Lichenoid drug eruption
             
  Lichen Nitidus: click
                Lichen Striatus
                
II-  Vacuolar (Erythema Multiforme-like) Reaction:

        Eg-    Erythema Multiforme
                 Toxic epidermal necrolysis
                 Acute graft vs host disease
(Cutaneous lesions in graft versus host disease: click)
                 Pityriasis lichenoides
                 Lupus erythematosus (acute & subacute)
                 Fixed drug eruption 
(Drug induced cutaneous lesions: click)
                
III-   Atrophic (Poikilodermatous) Reaction:


        Eg-     Atrophic lichen planus
                  Systemic lupus erythematosus
                  Dermatomyositis
                  Mycosis Fungoides
                  
IV-  Interface Reactions with Irregular Epidermal Hyperplasia:
      
        Eg-      Hypertrophic lichen planus       
                   Rare lichenoid drug eruptions
                   Verrucous lupus erythematosus

V-    Interface Reactions with Psoriasiform Hyperplasia
         
        Eg-      Pityriasis lichenoides
                    Mycosis fungoides
                    Secondary syphilis
                    Lichen aureus

Histopathology Images of Lichen Planus: 

Image Link1   ; Image Link2   ;

Image Link3 .

                     

 

Granulomatous Reaction Pattern of the Skin

Granuloma Annulare

Necrobiosis Lipoidica

Necrobiotic Xanthogranuloma   

Rheumatoid Nodule

Lupus Vulgaris

Cutaneous Sarcoidosis

Melkersson Rosenthal Syndrome

Annular Elastolytic Giant Cell Granuloma

Skin lesion in Crohn's Disease

Blastomycosis-like pyoderma

Foreign body granuloma

Rosacea

Interstitial Granulomatous Dermatitis

Interstitial Granulomatous Drug Reaction

Granulomatous T-cell lymphoma

Toxic Shock Syndrome

Cutaneous lesion in graft-versus host disease

Pathology of the Eyelid

Inflammatory diseases of the Eyelid

Tumour and tumour-like lesions of the Eyelid

Adnexal Tumours of the eyelid

Epidermal tumours of the Eyelid

Mesenchymal Tumours of the Eyelid

Melanocytic tumours of the Eyelid


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