 Site created by Dr Sampurna Roy MD
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Dr Sampurna Roy
MD
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Surgical-Pathology.com
Environmental Pathology Online
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Interface dermatosis is a common form of inflammatory dermatosis. A wide
range of inflammatory skin diseases exhibit interface change with
considerable overlap of histological features. The term "lichenoid" is avoided by some pathologists because of clinical and histological difference in the definition of this term. The following features are characteristic of interface dermatitis: I- Mild or dense inflammatory infiltrate composed of mainly mononuclear cells. This feature is essential to make a diagnosis of an interface dermatitis. II- Vacuolar or hydropic change due to basal cell degeneration. III- Colloid or civatte bodies are eosinophilic bodies formed as a result of apoptosis. These may be present in the lower part of the epidermis (suprabasal) or in the dermis. IV- Pigment incontinence due to damage of basal keratinocytes and melanocytes.
Histopathology Images of Lichen Planus:
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Granulomatous Reaction Pattern of the Skin
Annular Elastolytic Giant Cell Granuloma Skin lesion in Crohn's Disease Interstitial Granulomatous Dermatitis |
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Pathology of the Eyelid Inflammatory diseases of the Eyelid Tumour and tumour-like lesions of the Eyelid Epidermal tumours of the Eyelid |