In the GI tract the commonest site of the lesion is stomach.

Clinical presentation:  The patient presents with dysphagia, hemorrhage or gastro-esophageal reflux symptoms. Laryngeal impaction may cause death due to asphyxia.

Site:  Located in the mid or distal third of the esophagus.  Usually submucosal, solitary lesion which grows intraluminally.

Gross:  Polypoid mass  which involves the full thickness of the esophagus. The lesion may infiltrate into the surrounding tissue. It should not be mistaken for a malignant tumour.

Microscopic feature:  Characterized by fibrous stroma with prominent blood vessels and predominantly an eosinophilic inflammatory infiltrate. Variable numbers of mononuclear cells, plasma cells, mast cells and neutrophils are present. There is some stromal edema. Overlying epithelium is  ulcerated in some cases.

Differential diagnosis: i)Leiomyoma (consists of neoplastic smooth muscle fibres) ii) Fibrovascular polyp of the esophagus (mature fibrous tissue, thin walled blood vessels, adipocytes often present).                           

Abstracts:

Inflammatory fibroid polyp of the oesophagus.World J Surg Oncol. 2005 May 30;3:30.

Inflammatory fibroid polyps of the gastrointestinal tract: clinical, pathologic, and molecular characteristics. Appl Immunohistochem Mol Morphol. 2004 Mar;12(1):59-66.

Recurrent inflammatory fibroid polyp of cardia: a case report.World J Gastroenterol. 2004 Mar 1;10(5):767-8.

Rare case of inflammatory fibrous polyp of the esophagus.Dis Esophagus. 2002;15(4):326-9.

Inflammatory fibroid polyp of the esophagus.Dis Esophagus. 2000;13(1):75-9.

Inflammatory fibroid polyp of the esophagus in an HIV-infected individual: case study.Dysphagia. 1995 Winter; 10(1) :59-61.

Esophageal inflammatory fibroid polyp. Endoscopic and radiologic features.Dig Dis Sci. 1994 Dec;39(12):2561-6.

Inflammatory fibroid polyps of the gastrointestinal tract. An immunohistochemical and electron microscopic study.Cancer. 1983 May 1;51(9):1682-90.

Inflammatory pseudotumors (Inflammatory fibrous polyps) of the oesophagus: a clinicopathologic study.
Am J Digestive Dis 1975, 20:475-481

 

Soft Tissue Pathology; Myxoid Tumours of Soft Tissue ;  Classification of Soft Tissue Tumour;  Gross examination of soft tissue specimen ;  A practical approach to histopathological reporting of soft tissue tumours ;  Grading of soft tissue tumours ; Lipomatous tumours ;Neural tumours ; Myogenic tumours ;Vascular tumours ; Fibroblastic/ Myofibroblastic tumours ; Myofibroblastic tumours ;  Fibrohistiocytic tumours ; ChondroOsseous tumours ; Soft TissueTumours of Uncertain Differentiation ; Notochordal Tumour -Chordoma ;Extra-adrenal Paraganglioma ; Gastrointestinal Stromal Tumour ;

AN APPROACH TO THE  REPORTING  OF ESOPHAGEAL BIOPSIES

BARRETT'S   ESOPHAGUS   (INTESTINAL METAPLASIA  DYSPLASIA  &   ADENOCARCINOMA)

BENIGN TUMOURS AND  TUMOUR - LIKE CONDITIONS  OF  ESOPHAGUS

 1. SQUAMOUS PAPILLOMA OF THE ESOPHAGUS

 2. INFLAMMATORY FIBROID POLYP OF THE ESOPHAGUS

 3. LEIOMYOMA OF THE ESOPHAGUS

 4. GRANULAR CELL TUMOUR OF THE ESOPHAGUS

 5. ESOPHAGEAL CYSTS

 6. GLYCOGENIC ACANTHOSIS

 7.FIBROVASCULAR POLYPS

REPORTING  OF  ESOPHAGEAL  RESECTION SPECIMENS

SQUAMOUS  EPITHELIAL  DYSPLASIA INCLUDING SQUAMOUS CELL CARCINOMA IN-SITU OF THE ESOPHAGUS

SMALL CELL CARCINOMA OF THE ESOPHAGUS

DRUG  RELATED  LESIONS  OF  THE GASTROINTESTINAL TRACT