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Microcystic Adnexal Carcinoma

  Dr  Sampurna Roy  MD

 


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Polyps of the intestine are very common specimen and represent a large proportion of the practising pathologists' workload in any part of the world.

There are many types of intestinal polyps and accurate histological assessment is important to ensure the accurate diagnosis and appropriate management of the patients.

Any localized lesion raised above an epithelial surface may be regarded as a polyp. Polyps can arise from mucosal and submucosal tissues.

Polyps can be formed as a result of abnormal mucosal maturation, inflammation or architecture. These polyps are non-neoplastic and do not have malignant potential per se. Examples- Hyperplastic polyps ; Juvenile polyps ; Peutz Jeghers polyps.

The polyps that arise as a result of proliferative dysplasia are termed as adenomatous polyps or adenomas. They are true neoplastic lesions and are precursors of carcinoma.

In addition to adenomatous polyps a number of other neoplasms such as carcinoid tumour, primary lymphoma, stromal tumour, Kaposi's sarcoma and occasionally carcinoma can present as colorectal polyps.
The term polyposis should be restricted to recognizable syndromes in which the primary feature is the presence of multiple polyps.

Diagnosis of Path Quiz Cases:

Case 47 - Juvenile Polyp-  Image1 ; Image2; Image3 ; Image4.

Case 48 - Peutz-Jeghers Polyp- Image1 ; Image2; Image3 ; Image4 ; Image5.

Case 49 - Inflammatory Fibroid  Polyp-  Image1 ; Image2; Image3 ; Image4 ; Image5.
Case 50 - Multiple Lymphomatous Polyposis-
Image1 ; Image2; Image3 ; Image4.
Case 51 - Lymphoid  Polyp-
Image1 ; Image2; Image3 ; Image4.

                   

AUDIO/ VISUAL SLIDE PRESENTATIONS:

Juvenile Polyp and polyposis: click here

Peutz-Jeghers Polyp: click here

Inflammatory Fibroid Polyp: click here

Benign Lymphoid Polyp and Malignant Lymphomatous polyposis: click here

Note: Each presentation may take several minutes to download when you are using  a dial-up modem, so please be patient.
After the download is complete click on the 'audio icon' on each slide to listen to the lecture.

Classification of polyps and polyposis syndromes of intestine:  [ Ref:  Curr.Diagn.Pathol (1997) 4, 222-238]

         Polyp    Pathogenesis Polyposis syndrome     
Adenoma           neoplasia       Familial adeno. polyposis(FAP)
Juvenile polyp hamartoma   Juvenile Polyposis         
Peutz-Jeghers polyp hamartoma  Peutz-Jeghers syndrome     
Hyperplastic polyp   ? hypermaturity Hyperplastic polyposis
Inflammatory polyp                                       inflammation          Inflammatory polyposis
Polypoid mucosal prolapse     (including inflammatory cloacogenic, cap and inflammatory myoglandular
  polyps)   
               
mucosal prolapse  Cap polyposis
Lymphoid polyp      hyperplasia           Lymphoid polyposis   
Lymphomatous polyp       neoplasia     Malignant lymphomatous polypsis
Inflammatory fibroid polyp ? trauma     Inflammatory fibroid polyposis

Immuno. profile of Mantle cell lymphoma & MALT Lymphoma

                 

 
August 2009
  Gastrointestinal Stromal Tumour

   

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