Gastrointestinal Stromal Tumour

   

www.histopathology-india.net/GIPath.htm

                          HISTOPATHOLOGY INDIA.COM

 Adult Respiratory Distress Syndrome

    Dr  Sampurna Roy  MD

 
Web www.histopathology-india.net
 DermPath-India

        

http://www.histopathology-india.net/LargeIntestinePath.htm

April 2007
Surgical-Pathology.com

Histopathology-India.net

Eye Pathology Online

Cardiac Path Online;

Pulmonary Pathology Online

Pathology Quiz Online;

Dermpath-India;

GI Path Online

Mesothelioma-Online;

Soft Tissue Pathology;

Case Index

Infectious Disease Online; INDEX: A-D ; INDEX: E-L ; INDEX: M-P INDEX: Q-Z ; FUNGAL DISEASE ; VIRAL DISEASE.

NORMAL HISTOLOGY OF ESOPHAGUS

AN APPROACH TO THE  REPORTING  OF ESOPHAGEAL BIOPSIES

BARRETT'S   ESOPHAGUS   (INTESTINAL METAPLASIA  DYSPLASIA  &   ADENOCARCINOMA)

BENIGN TUMOURS AND  TUMOUR - LIKE CONDITIONS  OF  ESOPHAGUS

 1. SQUAMOUS PAPILLOMA OF THE ESOPHAGUS

 2. INFLAMMATORY FIBROID POLYP OF THE ESOPHAGUS

 3. LEIOMYOMA OF THE ESOPHAGUS

 4. GRANULAR CELL TUMOUR OF THE ESOPHAGUS

 5. ESOPHAGEAL CYSTS

 6. GLYCOGENIC ACANTHOSIS

REPORTING  OF  ESOPHAGEAL  RESECTION SPECIMENS

SQUAMOUS  EPITHELIAL  DYSPLASIA INCLUDING SQUAMOUS CELL CARCINOMA IN-SITU OF THE ESOPHAGUS

SMALL CELL CARCINOMA OF THE ESOPHAGUS

Assessment of the Intestinal abnormalities - lumen, surface epithelium and the subepithelial  zone : click

Assessment of the Intestinal abnormalities :crypt density, architecture and epithelium : click

Assessment of abnormalities :changes in the lamina propria, muscularis mucosae and submucosa ): click  

 

Normal Histology of the Large Intestine

Interpretation of Large Intestinal Biopsies

Microscopic/collagenous colitis     

Pseudomembranous colitis

Pathology of Amebic Colitis  

Eosinophilic Gastroenteritis

Drug related lesions of the Gastrointestinal Tract

         

Non-neoplastic Colorectal diseases:
Complicated diverticular disease
Ulcerative colitis CLICK
Crohn's disease
Ischaemic colitis
Volvulus
Angiodysplasia
Motility disorders
Radiation colitis
Note: Specimen dissection and block selection depends on the specific pathology.

Blocks:
Sections are taken at each 10cm distance from the proximal to distal resection margins.
Sampling of any focal lesion.
Sections of the resection margins or doughnuts (in ulcerative colitis to rule out dysplasia).
Any stricture should be sampled to rule out malignancy.
Lymphnodes should be sampled (no need to embed all nodes)

                

Handling and preservation of freshly received specimen in the lab:

- The pathologist should examine the serosal surface of the unopened fresh specimen (look for fistula or perforation)
- Specimen is opened throughout its length along the antimesenteric wall (including any stricture).
- Faeces  blood and mucus removed by gentle washing in cold running water.
- Resection specimen pinned to cork board and fixed for atleast 48 hrs.
- Specimen may be unpinned and floated free in fixative after initial 24 hrs.


Gross description of the specimen:
Description should include the nature of specimen (extent of surgical resection).
Record the nature, extent & distribution of changes in non-neoplastic lesions.

Record the following features:

-Serosa - fibrin, pus, fibrosis, adherence of mesentery
-Distribution of serosal fat wrapping
-Mural thickening
-Severe dilatation (toxic megacolon)
-Stricture formation
-Ulcers (linear or transverse)
-Mucosal cobblestoning 
-Perforation
-Pseudopolyps
-Hemorrhage
-Fissures
-Any suspicious neoplastic lesion

Visit: Gross examination of polypectomey specimens

Pathology of the Intestinal Polyps ;Hyperplastic polyps and serrated adenomas ; Inflammatory polyps/Inflammatory cap polyps / Polypoid mucosal polyps ;Juvenile polyp ; Peutz-Jeghers polyp ; Inflammatory fibroid polyp ; Multiple Lymphomatous polyposis ;Lymphoid polyp;
 
Web www.histopathology-india.net

 CLICK ON THE IMAGES


An outline of the anatomy and normal histology of the  stomach for pathologists.

Reporting of gastric biopsies (non-neoplastic gastric lesions).

Pathology and pathogenesis of peptic ulcer.

Acute Gastritis 

Chronic Gastritis

Helicobacter pylori  associated(TypeB) Gastritis 

Autoimmune Gastritis (Type A) 

Reactive /Reflux/ Chemical Gastritis (Type C)

Lymphocytic Gastritis

Collagenous Gastritis

Granulomatous Gastritis

Eosinophilic Gastritis

Gastric Xanthoma/Xanthelasma

Other Non-Neoplastic Gastric Lesions

Benign tumour and tumour- like lesions

Gastric Lymphoma

Gastric Carcinoid Tumour

Gastrointestinal Stromal Tumour 

Gastric Epithelial Dysplasia

Early Gastric Carcinoma

Gross Examination of the Gastrectomy Specimen