Site created by

 Dr Sampurna Roy MD

http://www.histopathology-india.net/dermpath.htm

        Median Raphe Cyst

      Dr Sampurna Roy MD

 

Custom Search

Dermatopathology Case 108

Median raphe cyst is a very rare, benign congenital lesion occurring mainly on the ventral aspect of the penis, but can develop anywhere in the midline between the external urethral meatus and anus. It is most common near the glans penis.

They are thought to arise as a result of defective embryological closure of the median raphe, but some may result from the anomalous outgrowth of the entodermal urethral lining (urethroid cyst).

Median raphe cyst may be formed as a result of local trauma or secondary infection.

Gross presentation:  These cysts are usually less than 1 cm in diameter.

The contents are usually clear, but they may be turbid if there is abundant mucous glands in the wall.

Histopathology:  Images

Median raphe cysts are usually located in the dermis.

These lesions do not connect with the overlying surface epithelium.

The cysts  are lined by pseudostratified columnar epithelium.

In some areas they may be quite attenuated.

Occasionally, mucous glands are present in the wall, but ciliated cells are rare.

Pigmented cysts, resulting from the presence of melanocytes, have been reported.

In cysts situated near the meatus, the lining is usually stratified squamous epithelium.

Canal-like median raphe cysts: an unusual presentation of an unusual condition.Clin Exp Dermatol. 2009 Dec;34(8):e857-8. Epub 2009 Oct 10.

Median raphe cyst. Report of two cases and literature review.Arch Esp Urol. 2009 Sep;62(7):585-9.

Median raphe cysts of the perineum in children. Urology. 2008 May;71(5):830-1. Epub 2008 Mar 3.

Ciliated median raphe cyst of perineum presenting as perianal polyp: a case report with immunohistochemical study, review of literature, and pathogenesis.ScientificWorldJournal. 2006 Mar 5;6:2339-44.

Immunohistochemical characterization of a median raphe cyst of the penis.Ann Pathol. 1994;14(3):174-6.

Median raphe cysts of the penis.Arch Dermatol. 1979 Sep;115(9):1084-6.

Custom Search

Furuncle(Boil)

Carbuncle

Toxic Shock Syndrome

Allergic Granulomatosis (Churg-Strauss Syndrome)

Cutaneous Ciliated Cyst

Infective Panniculitis

Pancreatic Panniculiti

Cutaneous Deposits

Calcinosis Cutis

Cutaneous Ossification (Osteoma Cutis)

Cartilaginous lesions of skin

Lipoid Proteinosis

Pathology of Colloid Milium

Gout

Silicone granulomas

Drug related cutaneous lesions

Cutaneous lesion in graft-
versus host disease

Cutaneous lesions after exposure to Radiation