DermPath-India

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 Dr Sampurna Roy MD

          

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       Desmoplastic/Spindle cell
/Neurotropic Melanoma

        Dr. Sampurna Roy  MD

 
 Melanocytic Tumours

http://www.histopathology-india.MelanocyticTumours.htm

June 2009
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Melanocytic tumours
              
1. Acquired Melanocytic Naevus

Ancient Naevus 
Halo naevus 
Balloon cell naevus 
Combined Naevus 
Recurrent melanocytic naevus 
                   
2. Spindle and epithelioid cell naevi

Spitz naevus
Pigmented spindle cell naevus

3. Blue naevi

Common blue naevus 
Cellular blue naevus


4. Dermal melanocytoses

Naevus of Ota

Naevus of Ito   
Mongolian spot  

5. Congenital melanocytic naevi                                           
6. Dysplastic melanocytic naevi

Pathology of the Eyelid

Inflammatory diseases of the Eyelid

Tumour and tumour-like lesions of the Eyelid

Adnexal Tumours of the eyelid

Epidermal tumours of the Eyelid

A number of paucicellular melanocytic intradermal proliferations often occur in Asian individuals.

'Dermal melanocytosis' is commonly used as a term in any situation where there are melanocytes within the dermis. 

Small number of melanocytes may be a feature of normal skin in some sites of the body.

        

DermAtlas- Image Links1   2   3   4

PUB MED: ARTICLES RELATED TO OTA'S AND ITO'S NEVUS
PUB MED: ARTICLES RELATED TO  MONGOLIAN SPOTS
                      MONGOLIAN SPOT

This dermal melanocytic lesion presents as slate coloured patches of discolouration.

Mongolian spots are usually seen in Orientals. It is present at birth or appears in early infancy and usually disappears in childhood. 

Site:  Located at the sacrococcygeal region as well as in the scalp and temple.

Microscopic features:  Histopathology reveals scattered slender melanin containing  melanocytes orientated horizontally in the deep part of the reticular dermis together with a few melanophages.
                                 Image Link

                 

   NEVUS OF OTA AND NEVUS OF ITO

These dermal melanocytic conditions present as blue to dark brown macular area of pigmentation .

The  nevus of Ota  is usually located in the  region of opthalmic and maxillary division of the trigeminal nerve. The conjunctiva may also be involved. Ota's nevus may be associated with oral, uveal or leptomeningeal melanosis and malignant transformation has been reported repeatedly.

The nevus of Ito is usually located in the supraclavicular and deltoid region.

Histologically there are nodular and diffuse collection of melanocytes. These are scattered in the upper parts of the reticular dermis.  The appearances resemble those of blue naevus.

In contrast to Mongolian spot these hyperpigmentations do not disappear.
      

  
 Nevus of Ito-     Image Link1 ;  2

   Nevus of Ota-    Image Link
 


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Pigmented melanocytic lesions causing diagnostic problems

Prognostic parameters of melanoma

Lentigo maligna melanoma

Superficial spreading melanoma

Nodular melanoma

Acral lentiginous melanoma

Desmoplastic /Spindle cell /
Neurotropic melanoma

Naevoid melanoma

Balloon cell melanoma

 

Mesenchymal Tumours of the Eyelid

Melanocytic tumours of the Eyelid

Epidermal tumours

Epidermal Naevus

Prurigo Nodularis

Acanthomas

Clear cell acanthoma

Large cell acanthoma

Warty Dyskeratoma

Seborrheic Keratosis

Verruca vulgaris;

Keratoacanthoma

Actinic Keratosis

Bowen's disease

Basal Cell Carcinoma

Squamous Cell Carcinoma

Cutaneous Squamous Cell Carcinoma (Image &abstracts)

Verruciform Xanthoma

Cutaneous infection and infestations

Histopathological patterns in cutaneous infections


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