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Pulmonary Pathology Online

Chronic Obstructive Pulmonary Disease

Dr Sampurna Roy MD 





Diffuse pulmonary disease is classified as:

1) Obstructive disease, characterized by increased resistance to airflow.

2) Restrictive disease characterized by reduced expansion of lung parenchyma, with decreased total lung capacity.

Chronic obstructive pulmonary disease (COPD) is a major health problem.

The disease is driven by abnormal inflammatory reactions in response to inhaled particles and fumes.

Therefore, inflammatory mediators are postulated to be of distinct importance.

Chronic obstructive pulmonary disease (COPD) is a spectrum of clinical disease from pure emphysema to pure bronchitis.

There are certain differences between two extremes but many individuals show overlapping features due to common initiating factor, cigarette smoking.

Obstructive Lung Disease:

-  Emphysema

-  Chronic bronchitis

-  Asthma

-  Bronchiectasis


Systemic inflammation in COPD: is genetic susceptibility a key factor?

Chronic obstructive pulmonary disease and sleep: the interaction.

The role of airway secretions in COPD--clinical applications.

TNF-alpha-, TNF-beta-, IL-6-, and IL-10-promoter polymorphisms in patients with chronic obstructive pulmonary disease.




Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)


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