Path Case20

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June 2004 Case - 20

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Clinical History: A 31 year old male with a long history of recurrent, crusted plaque

                  in the right axilla.

                   Histological features: (click on the images)

                      - Broad, acantholytic suprabasal vesicle.

- Prominence of acantholytic keratinocytes.

- Intercellular edema causing partial acantholysis giving the characteristic 'dilapidated brick wall'

appearance.

- Occasional dyskeratotic cells are present.

- There is downward elongation of rete ridges.

- Papillae covered by keratinocytes (villi) protrude into the bulla.

DIAGNOSIS:

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