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Pathology Quiz Online

Pathology Quiz Case - 41

Dr Sampurna Roy MD





Clinical History:   A 65 year old female with a bullous lesion on the flexor surface of  the left upper arm.

Microscopic features :  Skin biopsy in which the epidermis is flattened with no evidence of necrotic keratinocytes.  

There is a large subepidermal bulla, the lumen of which contains numerous eosinophils together with a few lymphocytes and neutrophils enmeshed with fibrin.

In areas the papillary dermis festoons into the blister cavity. 

The underlying dermis is oedematous and shows a patchy chronic inflammatory infiltrate.















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