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Pathology Quiz Online

Pathology Quiz Case - 45

Dr Sampurna Roy MD




Clinical History:  A 55 year old female with a rapidly growing palpable tender solitary mass of 2 months duration, in the triceps muscle of the left arm.

The lesion is 3 cm in diameter. There is no history of trauma.

Gross features:  Poorly demarcated firm scarlike induration (3 cm x 2.5 x 0.5) involving muscle and overlying muscle fascia.

Clues to diagnosis: Alternating areas of well preserved muscular fibres and strands of  proliferating spindle shaped cells (checkerboard- pattern).

Uni and binucleated ganglion-like cells.

Immunohistochemistry: Spindle cells are positive for smooth muscle actin but negative for desmin.

Ganglion-like cells are positive for vimentin but negative for smooth muscle actin and desmin.


















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