Pathology Quiz Online

                                April 2005     Case - 51

                                                  Dr  Sampurna Roy  MD 

               Clinical History: A 25 year old male presented with abdominal pain.

           Barium enema x-ray and colonoscopy revealed large sessile polyps in the rectum.

           These are H & E sections from the rectal polyp.

           Immunohistochemistry:   Lymphoid follicle (germinal centres) - CD20 (L26)- positive B-cells

           Interfollicular area - CD3 and CD45RO (UCHL1)-positive T-cells.

           Germinal centres -  B-cells are negative for BCL-2 .

                              DIAGNOSIS: