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Pathology Quiz Online

Pathology Quiz Case - 93

Dr Sampurna Roy MD




Clinical History:

A 45 year old woman died of congestive heart failure.  

At autopsy, her heart was slightly enlarged and the heart muscle was thickened with many small whitish nodules.




Note:   Granulomatous Inflammation of the Heart :   Reference: 

- Diseases showing well-developed granulomas : Disease caused by infective agents (tuberculosis, fungal and parasitic disorders ) ;  Sarcoidosis  ;  Giant cell myocarditis ;  A reaction to foreign bodies and devices implanted within the cardiovascular system.

- Rheumatic Fever : Specific lesion characterized by granulomas known as Aschoff's nodules.

- Metabolic disorders :  Granulomas occur in Farber's disease (lipogranulomatosis)  ; Gout (in which tophi are associated with calcific deposits and with a foreign body cellular reaction)  ;  Various syndromes of oxalosis (in which oxalate deposits also lead to a foreign body reaction)  ;  In chronic granulomatous disease of childhood.

- Other conditions showing Foreign body giant cells :  In association with calcification of necrotic myocytes and in the syndromes of "cholesterol pericarditis".

What is the diagnosis of Case No 93 ?













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