Custom Search

       

Dermpath-India

Pathology of Papillary Eccrine Adenoma

Dr Sampurna Roy MD         

 

Dermatopathology Quiz Case 131

Diagnosis : Papillary Eccrine Adenoma

 

                                                                                                   

 

 

Papillary eccrine adenoma, a rare benign adnexal tumour, was first described in 1977. Papillary eccrine adenoma. Arch Dermatol. 1977;113(5):596-8.

Clinical presentation:  Firm or hard nodules, frequently of many years' duration, and a large proportion are situated on the extremities.

 
Microscopic features:

Symmetrical lesion ;

Tumour is composed of dilated duct-like structures of various sizes with intraluminal papillary projections ;

Ducts are lined by two or more layers of cells ;

Inner layer often forms one or multiple papillae of variable complexity ;

Lumina contains eosinophilic amorphous material ;

Fibrous stroma around the lesion is well separated from the surrounding dermis  ;

Stroma consists of patches of loosely arranged spindled cells and areas of hyalinized collagen.

Other features -  focal squamous differentiation ; clear cell change ; connection of ducts to the epidermis ; prominent nerves within the stroma.

'Tubulopapillary hidradenoma' is a term proposed to describe lesions with both eccrine and apocrine differentiation.

It encompasses a spectrum of lesions that includes tubular apocrine adenoma and papillary eccrine adenoma.

Immunohistochemistry:  

Demonstrated immunoreactivity to S-100 protein, carcinoembryonic antigen, and epithelial membrane antigen.

 

Differential diagnosis: The differential diagnosis includes other cutaneous neoplasms with intraductal papillary proliferation.

 

Further reading:

Papillary eccrine adenoma in association with cutaneous horn.

Papillary eccrine adenoma should not be mistaken for aggressive digital papillary adenocarcinoma.

Papillary eccrine adenoma.

Papillary eccrine adenoma of the heel: a case report.

Papillary eccrine adenoma: immunohistochemical study and literature review.

Papillary eccrine adenoma: an ultrastructural and immunohistochemical study.

Papillary eccrine adenoma: immunohistochemical studies of keratin expression.

Papillary tubular adenoma with marked tubular vacuolization. 


 

 

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)


 

Histopathology-India.net

 

Pathopedia-India.com

 

Surgical Pathology.com

 

Pathology-India.com

 

Dermpath-India

 

Infectious Disease Online

 

Pathology Quiz Online 

 

Paediatric Pathology Online

 

Pancreatic Pathology Online

 

Paraganglioma-Online

 

Endocrine Pathology Online

 

Eye Pathology Online

 

Ear Pathology Online

 

Cardiac Path Online

 

Pulmonary Pathology Online

 

Lung Tumour Online

 

Mesothelioma-Online

 

Nutritional Pathology Online

 

Environmental Pathology Online

 

Soft Tissue Tumour Online

 

GI Path Online-India

 

Gallbladder Pathology Online

 

E-book - History of Medicine  

 

Microscope - Seeing the Unseen

 

 

 

Disclaimer

Privacy Policy  

Advertising Policy

Copyright 2017  histopathology-india.net