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Skin Appendage Tumour
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Papillary Eccrine Adenoma
Dr Sampurna Roy
MD
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Dermpath-India Site created by Dr Sampurna Roy MD
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Benign sweat gland tumours Cysts: Hydrocystoma -Eccrine/Apocrine Porokeratotic eccrine ostial naevus Benign Neoplasms: Syringocystadenoma Papilliferum Chondroid Syringoma (benign mixed tumour) Low grade: Primary extramammary Paget’s disease Intermediate grade: Digital papillary adenocarcinoma High grade: |
| Sebaceous tumours |
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Cutaneous infection and infestations Histopathological patterns in cutaneous infections : Bacterial, Rickettsial and Chlamydial infection |
Papillary eccrine adenoma, a rare benign adnexal tumour, was first described in 1977. Papillary eccrine adenoma. Arch Dermatol. 1977;113(5):596-8. Clinical presentation: Firm or hard nodules, frequently of many years' duration, and a large proportion are situated on the extremities of black persons. Microscopic features:
Symmetrical lesion ; Tumour is composed of dilated duct-like structures of various sizes with intraluminal papillary projections ; Ducts are lined by two or more layers of cells ; Inner layer often forms one or multiple papillae of variable complexity ; Lumina contains eosinophilic amorphous material ; Fibrous stroma around the lesion is well separated from the surrounding dermis ; Stroma consists of patches of loosely arranged spindled cells and areas of hyalinized collagen. Other features - focal squamous differentiation ; clear cell change ; connection of ducts to the epidermis ; prominent nerves within the stroma. Tubulopapillary hidradenoma' is a term proposed to describe lesions with both eccrine and apocrine differentiation. It encompasses a spectrum of lesions that includes tubular apocrine adenoma and papillary eccrine adenoma. Immunohistochemistry: Demonstrated immunoreactivity to S-100 protein, carcinoembryonic antigen, and epithelial membrane antigen. Differential diagnosis: The differential diagnosis includes other cutaneous neoplasms with intraductal papillary proliferation. |
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Histopathology-India.net
diagnostichistopathology. blogspot.com Environmental Pathology Online
E-book - History of Medicine with special reference to India. |
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Myxoid
Tumours of Soft Tissue Classification of Soft Tissue Tumour Gross examination of soft tissue specimen A practical approach to histopathological reporting of soft tissue tumours Grading of soft tissue tumours Fibroblastic/Myofibroblastic tumours |