Cardiac Path Online

Histopathology reporting of the Specimens of Pericardium   

Dr Sampurna Roy MD

 

                                                                                                                      

 

Specimens of pericardium includes full thickness biopsies, pericardiectomy specimens for tuberculosis, sarcoidosis and other inflammatory conditions, and excisions for rare neoplasms such as teratoma and mesothelioma.

The diagnosis of malignant mesothelioma should be made with caution because it is a rare lesion and reactive mesothelial proliferation can be very florid in inflammatory conditions of the pericardium.

Clinical details of the patient:

Age and sex of the patient ; Presenting features and their duration ; History of exposure to asbestos, previous or current tuberculosis, sarcoidosis, systemic malignancy, uraemia, collagen vascular disease;

History of previous surgery, trauma, radiotherapy ;

Investigation : Radiological features and diagnosis , results of microbiological investigations and tuberculin test if relevant.

The pathologist should comment on the following features in the histopathology report:

- Mesothelial proliferation and hyperplasia : Which in severe cases can be mistaken for neoplasia ;

- Inflammation :

(i) Nature: acute, purulent, fibrinous, chronic non- specific, granulomatous, eosinophilic.

(ii) Severity

(iii) whether organisms are found ;

- Fibrosis :  With or without calcification ;

- Neoplasia : 

- Primary :  Mesothelioma, whether monophasic or biphasic; 

- Metastatic : Usually from carcinoma of breast and lung, and less commonly melanoma and lymphoma.

Special stains:

- van-Gieson for fibrosis;

- Mucin stain in cases of suspected mesothelioma, metastatic adenocarcinoma ;

- Stains for organisms as appropriate (Ziehl-Neelsen, Gram, PAS, Grocott )

- Immunostains to distinguish mesothelioma from metastatic adenocarcinoma.

 

 

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)

 


 

 

Histopathology-India.net

 

Pathopedia-India.com

 

Surgical Pathology.com

 

Pathology-India.com

 

Dermpath-India

 

Infectious Disease Online

 

Pathology Quiz Online 

 

Paediatric Pathology Online

 

Pancreatic Pathology Online

 

Paraganglioma-Online

 

Endocrine Pathology Online

 

Eye Pathology Online

 

Ear Pathology Online

 

Cardiac Path Online

 

Pulmonary Pathology Online

 

Lung Tumour Online

 

Mesothelioma-Online

 

Nutritional Pathology Online

 

Environmental Pathology Online

 

Soft Tissue Tumour Online

 

GI Path Online-India

 

Gallbladder Pathology Online

 

E-book - History of Medicine  

 

Microscope - Seeing the Unseen

 

 roypath.in

 

 

Disclaimer

Privacy Policy  

Advertising Policy

Copyright 2017  histopathology-india.net