HISTOPATHOLOGY INDIA.COM

                                    Adult Respiratory Distress Syndrome

    Dr  Sampurna Roy  MD

 
Web www.histopathology-india.net
 

                   

Pinta is a contagious, mild, systemic, nonvenereal treponematosis caused by Treponema carateum, which is morphologically identical to Treponema pallidum.

The disease occus in the Caribbean area, Central America and parts of remote, arid inland regions and river valleys of the Tropical South America.

Mode of transmission:  Transmission, usually after long intimate contact, is by skin-to-skin inoculation.

Clinical presentation: Image1 ; Image2 .

The lesions of pinta are confined to the skin and become very extensive. These are usually located on the extremities.

There is often overlap between the three clinical stages. Initial lesions are erythematous maculopapules, which grow by peripheral extension and often coalesce.

The secondary lesions are widespread, long-lasting scaly plaques that show a striking variety of colours - red, pink, slate blue and purple.

These lesions merge with the late stage, in which depigmentation resembling vitiligo occurs, and sometimes there is epidermal atrophy.

Microscopic features:  Primary and secondary lesions are identical and show hyperkeratosis, parakeratosis and acanthosis.

There is exocytosis of inflammatory cells, sometimes with intraepidermal abscesses.

Hypochromic areas show loss of basal pigmentation with numerous melanophages in the upper dermis.

 The dermal infiltrate, like the other changes, is heavier in established than in early lesions and includes lymphocytes, plasma cells and sometimes neutrophils. The infiltrate is predominantly superficial and perivascular.

The treponemes can be demonstrated by silver methods - they are present mainly in the upper epidermis and are rarely found in the dermis.

Darkfield examination of exudate and serologic tests for syphilis are positive when the secondary lesions appear.

A single dose of long-acting penicillin is curative

              

Abstracts:

Overview of endemic treponematoses.Med Trop (Mars). 2006;66(1):15-20

Tropical dermatology: bacterial tropical diseases. J Am Acad Dermatol. 2006 Apr;54(4):559-78; quiz 578-80.

The endemic treponematoses.Microbes Infect. 2002 Jan;4(1):83-94.

Pinta in Austria (or Cuba?): import of an extinct disease? Arch Dermatol. 1999 Jun;135(6):685-8.

Nonvenereal treponematoses: yaws, endemic syphilis, and pinta.J Am Acad Dermatol. 1993 Oct;29(4):519-35; quiz 536-8.

Epidemiology of endemic non-venereal treponematoses.Bull Mem Acad R Med Belg. 1992;147(3-5):149-59; discussion 159-61

Your Banner

 
Web www.histopathology-india.net
May 2007
Surgical-Pathology.com

Histopathology-India.net

Eye Pathology Online

Cardiac Path Online;

Pulmonary Pathology Online

Pathology Quiz Online;

Dermpath-India;

GI Path Online

Mesothelioma-Online;

Soft Tissue Pathology;

Case Index

Infectious Disease Online; INDEX: A-D ; INDEX: E-L ; INDEX: M-P INDEX: Q-Z ; FUNGAL DISEASE ; VIRAL DISEASE.

Cutaneous lesion associated  with AIDS

Amoebiasis (Entamoeba histolytica)

Anthrax Infection

Avian Influenza  

Bacillary angiomatosis

Blackwater Fever

Blastomycosis

Bartonellosis

Candidosis

Coccidioidomycosis

Cryptococcosis

Cryptosporidium

Cytomegalovirus infection

Dengue

Dermatophytosis

Giardiasis