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A brief overview of some important Neoplastic and Non-Neoplastic Diseases of the Lung.

The site is created by:  Dr Sampurna Roy MD









Non-Neoplastic Pulmonary Diseases


Neoplastic Pulmonary Diseases


Anatomy and Histology of the Normal Lung and Airways


Examination of Pulmonary and Pleural biopsies


Useful Chromatic and Immunostains  in PulmonaryPathology


Percutaneous Needle and Trucut Biopsy Specimen


Bronchial Biopsy Specimen


Transbronchial Biopsy Specimen


Transbronchial Biopsy in Lung Transplant Recipients


Examination and Handling of Open Lung Biopsy Specimens


Lobectomy and Pneumonectomy Specimen


Histopathological reporting of Pulmonary Parenchymal Biopsies


Histopathological reporting of Pulmonary biopsies in cases of Idiopathic Pulmonary Fibrosis


Closed pleural biopsy for neoplasm or inflammatory lesions 


Open pleural biopsy and pneumonectomy or pleural stripping


Anatomical Distribution of Pulmonary Disease


Congenital Cystic Adenomatoid  Malformation


Bronchopulmonary Sequestration


Acute Respiratory Distress Syndrome


Neonatal Respiratory Distress Syndrome


Complications of Neonatal Respiratory Distress Syndrome




Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis)


Pathology of Eosinophilic Granuloma of the Lung


Pathological Diagnosis of Granulomatous Lung Diseases


Infectious Granuloma of the Lung


Non-necrotising Granulomatous Inflammation of the lung


An approach to Histopathological Examination of Pulmonary Granulomatous Inflammation


Chronic Obstructive Pulmonary Disease


Bronchial Asthma



Chronic Bronchitis





Idiopathic Pulmonary Fibrosis


Usual Interstitial Pneumonia (UIP)


Non-specific interstitial pneumonia (NSIP)


Desquamative interstitial pneumonia (DIP)


Respiratory bronchiolitis-interstitial lung disease (RBILD)


Acute interstitial pneumonia (AIP)/organizing diffuse alveolar damage DAD)


Lymphocytic Interstitial Pneumonia / Follicular Bronchiolitis


Lipid Pneumonia (Paraffinoma)


Nodular Pulmonary Amyloid (Amyloidoma)


Pulmonary Alveolar Proteinosis


Pulmonary Thromboembolism


Other forms of Pulmonary Embolism


Pulmonary Infarction


Pulmonary Hypertension


Pulmonary Collapse (Atelectasis) and Pneumothorax


Pulmonary Edema


Pulmonary Vasculitis


Wegener's Granulomatosis of the Lung


Churg-Strauss Syndrome (allergic granulomatosis)


Microscopic Polyangiitis


Isolated Pulmonary Capillaritis


Necrotizing Sarcoid Granulomatosis


Pulmonary Hemorrhage (Example. Goodpasture's Syndrome)








Coal Pneumoconiosis



Pulmonary Infection


Pulmonary Infections in immunocompromised patients


Viral Infection: Influenza (Orthomyxoviruses)


Parainfluenza Virus Infection


Cytomegalovirus infection


Respiratory syncytial virus infection






Chlamydia: Chlamydial Infection


Rickettsia: Q Fever (Coxiella burnetii)


Mycoplasma: Mycoplasma pneumonia


Bacterial Infection: Pneumococcal Pneumonia (Lobar Pneumonia)




Klebsiella pneumoniae


Haemophilus influenza Infection


Legionellosis (Legionnaires'Disease)


Staphylococcal Infection


Streptococcal Infection




Atypical Mycobacterial Infection


Mycobacterium Avium Intracellulare


Mycobacterium Kansasii Infection


Fungal Infection:

Histoplasmosis (Histoplasma Capsulatum)












Candidosis (Candidiasis)


Filamentous bacteria:





Infections caused by other organisms:

Pneumocystis Pneumonia






Atypical Pneumonia

Pulmonary Cytology 

Exfoliative Pulmonary Cytology


Squamous Cell Carcinoma




Bronchioloalveolar Cell Carcinoma


Small Cell Carcinoma


Large Cell Carcinoma


Carcinoid Tumours


Metastatic Tumours


Fine Needle Aspiration Cytology


FNAC -Squamous Cell Carcinoma and Adenocarcinoma


FNAC - Bronchioloalveolar Cell Carcinoma


FNAC - Small Cell Carcinoma


FNAC - Non Small Cell and Large Cell Carcinoma


FNAC - Carcinoid Tumours


Cytological Pitfalls in the Diagnosis of Lung Cancer


Role of cytopathology in the diagnosis benign pulmonary tumours


Role of Immunohistochemistry in the diagnosis of lung tumours


Role of cytopathology in the diagnosis of Opportunistic Infections




- Mesothelioma- Online


- Impressive Macroscopic Specimens for those in Love with Pulmonary Pathology   

Lung Tumour-Online


Bronchogenic carcinoma


Pulmonary Adenocarcinoma


Adenocarcinoma In Situ (Bronchioloalveolar Carcinoma)


Papillary Carcinoma


Mucinous (colloid) carcinoma


Pulmonary Squamous Cell Carcinoma


Spindle cell squamous carcinoma


Basaloid carcinoma


Lymphoepithelioma-like carcinoma


Pleomorphic carcinoma (spindle/giant cell carcinoma)


Large cell carcinoma


Pulmonary Lymphoproliferative Disease


Lymphomatoid  Granulomatosis


B-cell non-Hodgkin’s MALT  lymphomas


Post-Transplant Lymphoproliferative Disease


Pulmonary Mesenchymal Tumours


Primary Pulmonary Leiomyosarcoma


Primary Pulmonary Rhabdomyosarcoma


Primary Monophasic Synovial  Sarcoma of the Lung


Neurogenic Tumours of the Lung


Intrapulmonary Solitary Fibrous Tumour


Localized Fibrous Tumour of the  Pleura


Pulmonary Malignant Fibrous Histiocytoma


Bone and Cartilage- forming  Sarcomas of the Lung


Kaposi's Sarcoma and Angiosarcoma of the Lung


Epithelioid Hemangioendothelioma of the Lung




Pulmonary tumours derived from ectopic tissues


Primary Intrapulmonary Thymoma


Glomus Tumour of the Lung


Primary Malignant Melanoma of Bronchus


Pulmonary Paraganglioma


Ganglioneuroblastoma of the Lung


Minute Pulmonary Meningothelial-like Nodules and Pulmonary Meningioma


Germ Cell Tumours of the Lung (Teratoma and Choriocarcinoma)


Biphasic Epithelial/Mesenchymal Lung Tumours


Pulmonary Carcinosarcoma


Pulmonary Blastoma


Neuroendocrine tumours of  the Lung


Central Carcinoid Tumour


Peripheral Carcinoid Tumour


Atypical Carcinoid


Small Cell Carcinoma


Large Cell Neuroendocrine Tumour  


Diffuse idiopathic neuroendocrine cell hyperplasia (DIPNECH)


Pulmonary Carcinoid Tumorlet


Salivary Gland-Type Tumours


Adenoid Cystic Carcinoma


Acinic Cell Carcinoma (Fechner tumour)


Salivary Gland-Type Mixed Tumours


Mucoepidermoid Carcinoma


Pulmonary Epithelial-Myoepithelial carcinoma


Pulmonary Oncocytoma


Granular Cell Tumour of Bronchus


Sclerosing hemangioma


Clear cell 'sugar' tumour


Inflammatory pseudotumour


Chondroid Hamartoma


Alveolar Adenoma


Endobronchial Lipoma


Bronchial 'mucous gland' adenoma


Pulmonary Papillary Adenoma


Pulmonary Adenofibroma


Minute Pulmonary Meningothelial-like Nodules and Pulmonary Meningioma


Metastatic Tumours of the Lung




Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)

 Image credit : Pixabay






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