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A brief overview of some important Neoplastic and Non-Neoplastic Diseases of the Lung.

The site is created by:

Dr Sampurna Roy MD





Non-Neoplastic Pulmonary Diseases

Neoplastic Pulmonary Diseases

Anatomy and Histology of the Normal Lung and Airways

Examination of Pulmonary and Pleural biopsies

Useful Chromatic and Immunostains  in PulmonaryPathology

Percutaneous Needle and Trucut Biopsy Specimen

Bronchial Biopsy Specimen

Transbronchial Biopsy Specimen

Transbronchial Biopsy in Lung Transplant Recipients

Examination and Handling of Open Lung Biopsy Specimens

Lobectomy and Pneumonectomy Specimen

Histopathological reporting of Pulmonary Parenchymal Biopsies

Histopathological reporting of Pulmonary biopsies in cases of Idiopathic Pulmonary Fibrosis

Closed pleural biopsy for neoplasm or inflammatory lesions 

Open pleural biopsy and pneumonectomy or pleural stripping

Anatomical Distribution of Pulmonary Disease

Congenital Cystic Adenomatoid  Malformation

Bronchopulmonary Sequestration

Acute Respiratory Distress Syndrome

Neonatal Respiratory Distress Syndrome

Complications of Neonatal Respiratory Distress Syndrome


Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis)

Pathology of Eosinophilic Granuloma of the Lung

Pathological Diagnosis of Granulomatous Lung Diseases

Infectious Granuloma of the Lung

Non-necrotising Granulomatous Inflammation of the lung

An approach to Histopathological Examination of Pulmonary Granulomatous Inflammation

Chronic Obstructive Pulmonary Disease

Bronchial Asthma


Chronic Bronchitis



Idiopathic Pulmonary Fibrosis

Usual Interstitial Pneumonia (UIP)

Non-specific interstitial pneumonia (NSIP)

Desquamative interstitial pneumonia (DIP)

Respiratory bronchiolitis-interstitial lung disease (RBILD)

Acute interstitial pneumonia (AIP)/organizing diffuse alveolar damage DAD)

Lymphocytic Interstitial Pneumonia / Follicular Bronchiolitis

Lipid Pneumonia (Paraffinoma)

Nodular Pulmonary Amyloid (Amyloidoma)

Pulmonary Alveolar Proteinosis

Pulmonary Thromboembolism

Other forms of Pulmonary Embolism

Pulmonary Infarction

Pulmonary Hypertension

Pulmonary Collapse (Atelectasis) and Pneumothorax

Pulmonary Edema

Pulmonary Vasculitis

Wegener's Granulomatosis of the Lung

Churg-Strauss Syndrome (allergic granulomatosis)

Microscopic Polyangiitis

Isolated Pulmonary Capillaritis

Necrotizing Sarcoid Granulomatosis

Pulmonary Hemorrhage (Example. Goodpasture's Syndrome)




Coal Pneumoconiosis


Pulmonary Infection

Pulmonary Infections in immunocompromised patients

Viral Infection:

Viruses are a common cause of airway lesions but those that primarily affect the airways may also severely affect the lung parenchyma.

It is important to note that viral lung infections produce interstitial (rather than alveolar) pneumonia and diffuse alveolar damage.

Influenza (Orthomyxoviruses)

Parainfluenza Virus Infection

Cytomegalovirus infection

Respiratory syncytial virus infection



Chlamydia: Chlamydial Infection

Rickettsia: Q Fever (Coxiella burnetii)

Mycoplasma: Mycoplasma pneumonia

Bacterial Infection:

Pneumococcal Pneumonia (Lobar Pneumonia)


Klebsiella pneumoniae

Haemophilus influenza Infection

Legionellosis (Legionnaires'Disease)

Staphylococcal Infection

Streptococcal Infection


Atypical Mycobacterial Infection

Mycobacterium Avium Intracellulare

Mycobacterium Kansasii Infection

Fungal Infection:

Histoplasmosis (Histoplasma Capsulatum)






Candidosis (Candidiasis)

Filamentous bacteria:



Infections caused by other organisms:

Pneumocystis Pneumonia



Atypical Pneumonia

Pulmonary Cytology 

Exfoliative Pulmonary Cytology

Squamous Cell Carcinoma


Bronchioloalveolar Cell Carcinoma

Small Cell Carcinoma

Large Cell Carcinoma

Carcinoid Tumours

Metastatic Tumours

Fine Needle Aspiration Cytology

FNAC -Squamous Cell Carcinoma and Adenocarcinoma

FNAC - Bronchioloalveolar Cell Carcinoma

FNAC - Small Cell Carcinoma

FNAC - Non Small Cell and Large Cell Carcinoma

FNAC - Carcinoid Tumours

Cytological Pitfalls in the Diagnosis of Lung Cancer

Role of cytopathology in the diagnosis benign pulmonary tumours

Role of Immunohistochemistry in the diagnosis of lung tumours

Role of cytopathology in the diagnosis of Opportunistic Infections




- Mesothelioma- Online


- Impressive Macroscopic Specimens for those in Love with Pulmonary Pathology   

Lung Tumour-Online

Bronchogenic carcinoma

Pulmonary Adenocarcinoma

Adenocarcinoma In Situ (Bronchioloalveolar Carcinoma)

Papillary Carcinoma

Mucinous (colloid) carcinoma

Pulmonary Squamous Cell Carcinoma

Spindle cell squamous carcinoma

Basaloid carcinoma

Lymphoepithelioma-like carcinoma

Pleomorphic carcinoma (spindle/giant cell carcinoma)

Large cell carcinoma

Pulmonary Lymphoproliferative Disease

Lymphomatoid  Granulomatosis

B-cell non-Hodgkin’s MALT  lymphomas

Post-Transplant Lymphoproliferative Disease

Pulmonary Mesenchymal Tumours

Primary Pulmonary Leiomyosarcoma

Primary Pulmonary Rhabdomyosarcoma

Primary Monophasic Synovial  Sarcoma of the Lung

Neurogenic Tumours of the Lung

Intrapulmonary Solitary Fibrous Tumour

Localized Fibrous Tumour of the  Pleura

Pulmonary Malignant Fibrous Histiocytoma

Bone and Cartilage- forming  Sarcomas of the Lung

Kaposi's Sarcoma and Angiosarcoma of the Lung

Epithelioid Hemangioendothelioma of the Lung


Pulmonary tumours derived from ectopic tissues

Primary Intrapulmonary Thymoma

Glomus Tumour of the Lung

Primary Malignant Melanoma of Bronchus

Pulmonary Paraganglioma

Ganglioneuroblastoma of the Lung

Minute Pulmonary Meningothelial-like Nodules and Pulmonary Meningioma

Germ Cell Tumours of the Lung (Teratoma and Choriocarcinoma)

Biphasic Epithelial/Mesenchymal Lung Tumours

Pulmonary Carcinosarcoma

Pulmonary Blastoma

Neuroendocrine tumours of  the Lung

Central Carcinoid Tumour

Peripheral Carcinoid Tumour

Atypical Carcinoid

Small Cell Carcinoma

Large Cell Neuroendocrine Tumour  

Diffuse idiopathic neuroendocrine cell hyperplasia (DIPNECH)

Pulmonary Carcinoid Tumorlet

Salivary Gland-Type Tumours

Adenoid Cystic Carcinoma

Acinic Cell Carcinoma (Fechner tumour)

Salivary Gland-Type Mixed Tumours

Mucoepidermoid Carcinoma

Pulmonary Epithelial-Myoepithelial carcinoma

Pulmonary Oncocytoma

Granular Cell Tumour of Bronchus

Sclerosing hemangioma

Clear cell 'sugar' tumour

Inflammatory pseudotumour

Chondroid Hamartoma

Alveolar Adenoma

Endobronchial Lipoma

Bronchial 'mucous gland' adenoma

Pulmonary Papillary Adenoma

Pulmonary Adenofibroma

Minute Pulmonary Meningothelial-like Nodules and Pulmonary Meningioma

Metastatic Tumours of the Lung


Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)






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