Custom Search

        \

 

GI Path Online

Pathology of Reflux/Reactive/

Chemical Gastritis (Type C)

Dr  Sampurna Roy  MD

 

GI Path Online- Home Page  

Gastric Pathology - Home Page

 

                                                                                                                      

 

Etiology:

- Consumption of aspirin and other nonsteroidal anti-inflammatory drugs.

- Chronic alcohol ingestion

- Alkaline or bile reflux (abnormal pyloric sphincter function, previous surgical intervention).

- Uraemia

Microscopic features:

- Glandular elongation and tortuosity

- Mucin depletion

- Edema

- Hypercellularity of the gastric pits

- Foveolar hyperplasia

- Increased number of smooth muscle fibres in lamina propria.

- Villiform transformation of the mucosa.

- Regenerative (basophilic) glands with increased mitotic activity.

- Capillary congestion and vasodilation in superficial lamina propria.

- A few chronic inflammatory cells and occasional neutrophils.

- Usually there is no evidence of atrophy.

- Bile in the glands.

- Long standing bile reflux cases may be accompanied by erosions or intestinal metaplasia (including all its subtypes).

Note :  Reactive gastritis with erosions is the commonest cause of false positive diagnosis of dysplasia or carcinoma in the stomach.

Further reading:

Cell proliferation in type C gastritis affecting the intact stomach.

Bile reflux gastritis and intestinal metaplasia at the cardia. 

Reflux gastritis in gastroesophageal reflux disease: A histopathological study.

Bile reflux and intestinal metaplasia in gastric mucosa.

Gastritis in patients on non-steroidal anti-inflammatory drugs. 

Reflux gastritis in the intact stomach.  

Reflux gastritis: distinct histopathological entity?

 

GI Path Online- Home Page  

Gastric Pathology - Home Page

 

 

 

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)


 

 

Histopathology-India.net

 

Pathopedia-India.com

 

Surgical Pathology.com

 

Pathology-India.com

 

Dermpath-India

 

Infectious Disease Online

 

Pathology Quiz Online 

 

Paediatric Pathology Online

 

Pancreatic Pathology Online

 

Paraganglioma-Online

 

Endocrine Pathology Online

 

Eye Pathology Online

 

Ear Pathology Online

 

Cardiac Path Online

 

Pulmonary Pathology Online

 

Lung Tumour Online

 

Mesothelioma-Online

 

Nutritional Pathology Online

 

Environmental Pathology Online

 

Soft Tissue Tumour Online

 

GI Path Online-India

 

Gallbladder Pathology Online

 

E-book - History of Medicine  

 

Microscope - Seeing the Unseen

 

 roypath.in

 

Disclaimer

Privacy Policy  

Advertising Policy

Copyright 2017  histopathology-india.net