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Pathology of Recurrent Nevus

Dr Sampurna Roy MD     





Nevus may recur following inadequate excision (shave biopsy of the lesion) or after chronic irritation or laser therapy.

Age and sex - These lesions usully occur in women from 20 to 30 years of age.

Site - Most common sites are on the trunk (specifically, the back), followed by face and extremities.

Almost 50% of the lesions recur within 6 months.

Microscopic features:


(i) The lesion displays lentiginous and junctional theques above the dermal scar.

(ii) There are no epidermal ridges. 

(iii) Dermal fibrosis is present due to previous operative procedure.

(iv) Nevus cells are present in the deep dermis and at the edge of the scar.

(v)  In the scarred area a few scattered nevus cells (like fibroblasts) are present.

(vi) Usually HMB45 stains more prominently in the recurrent nevi than the original lesion. 

Further reading:

Recurrent melanocytic nevus: a histologic and immunohistochemical evaluation

Histogenesis of recurrent nevus.

Recurrent nevus phenomenon: a clinicopathologic study of 357 cases and histologic comparison with melanoma with regression

The recurrent nevus phenomenon: a history of challenge, controversy, and discovery

Recurrent melanocytic nevi: clinical and histologic review of 175 cases

The recurrence of nevi after incomplete removal

Low rates of clinical recurrence after biopsy of benign to moderately dysplastic melanocytic nevi

Persistent (recurrent) Spitz nevi: a histopathologic, immunohistochemical, and molecular pathologic study of 22 cases

Recurrent pigmented melanocytic nevus. A benign lesion, not to be mistaken for malignant melanoma.




Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)






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