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Pigmented spindle cell
nevus (Reed Nevus):
Pigmented spindle cell
naevus is regarded as a distinct entity and not part of spindle
cell variant of
Spitz naevus.
Clinically, these lesions present as symmetrical ,sharply circumscribed,
darkly pigmented nodule or papule ( usually less than 0.6 cm in
diameter).
Image1
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Image2
Histologically, the tumour consists of spindle shaped cells in nests
with formation interconnecting fascicles.
Image1
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Image2
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Image3
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Image4.
Prominent vertical
orientation of cells are noted. The tumour grows in an expansile. These
are heavily pigmented and contains melanophages.
Kamino bodies (similar to Spitz) are noted in pigmented spindle cell
naevus.
Junctional clefting is noted in some cases.
Differential diagnosis include melanoma. Unlike melanoma these are
symmetrical lesions and display maturation of cells in the deeper part
of the lesion. Pagetoid spread of cells is limited to the lower half of
the epidermis. Visit:
Dermpath-India
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