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Skin Adnexal (Appendage) Tumours

Dr Sampurna Roy MD

 

                                                                                                                      

 

The cutaneous appendages give rise to a wide range of tumours.

This rare group of tumours is characterised by variable degrees of differentiation toward one or more skin appendages

(Sweat gland- eccrine ; apocrine ; apoeccrine  ; Sebaceous glands and Hair follicle).

Various classifications have been proposed in the past. 

In view of the new histochemical and ultrastructural findings and reporting of new adnexal tumours these classifications have been modified by various authors.

Diagram of normal skin showing the skin appendages:

By  Dr. Sampurna Roy MD

 

 

Sebaceous Tumours

Ectopic Sebaceous Glands:

Fordyce's spot

Hamartomas and Hyperplasias:

Folliculosebaceous Cystic Hamartoma

Steatocystoma

Nevus Sebaceous of Jadassohn

Sebaceous Hyperplasia

Benign:

Sebaceous Adenoma

Sebaceoma

Malignant:

Sebaceous Carcinoma

Tumours with focal sebaceous differentiation:

Basal cell carcinoma (the term "basal cell carcinoma with sebaceous differentiation" should be used only for an otherwise conventional basal cell carcinoma with histological evidence  of sebaceous differentiation) ;  Squamous cell carcinoma ; Seborrheic keratosis.

 

 

Hair Follicle Tumour

Hair Germ Differentiation:

Trichoepithelioma 

Desmoplastic  Trichoepithelioma

Trichofolliculoma

Trichoblastoma

Cutaneous lymphadenoma
                           
Infundibular differentiation:

Trichoadenoma

Dilated Pore of Winer

Pilar Sheath Acanthoma

Tumour of Follicular Infundibulum

Outer root sheath differentiation:
                    

Trichilemmoma

Trichilemmal Carcinoma

Proliferating Trichilemmal Cyst (Pilar Tumour)

Matrical differentiation:
                  
Pilomatrixoma and Pilomatrix Carcinoma

 

 

Sweat Gland Tumour

Cysts:

Hydrocystoma -Eccrine/Apocrine

Hamartomas:

Eccrine/Apocrine naevus

Eccrine Angiomatous  Hamartoma

Porokeratotic eccrine ostial naevus

Benign Neoplasms:

Syringocystadenoma Papilliferum

Hidradenoma Papilliferum

Nipple Adenoma

Syringoma

Spiradenoma

Cylindroma

Chondroid Syringoma (benign mixed tumour)

Poroma

Hidradenoma

Apocrine adenoma

Papillary eccrine adenoma

Syringofibroadenoma

Malignant  Neoplasms

Low grade:

Microcystic adnexal carcinoma

Eccrine epithelioma

Adenoid cystic carcinoma

Mucinous carcinoma

Primary extramammary Pagetís disease

Intermediate grade:

Porocarcinoma

Digital papillary adenocarcinoma

High grade:

Hidradenocarcinoma

Apocrine adenocarcinoma

Eccrine ductal carcinoma

Spiradenocarcinoma

Malignant cylindroma

 

 

 

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)

 

  

                

                                                 

                                                                                                                               


 

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