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 Skin Adnexal (Appendage) Tumours

Dr Sampurna Roy MD

The cutaneous appendages give rise to a wide range of tumours.

This rare group of tumours is characterised by variable degrees of differentiation toward one or more skin appendages

(Sweat gland- eccrine; apocrine; apoeccrine  ; Sebaceous glands and Hair follicle).

Various classifications have been proposed in the past. 

In view of the new histochemical & ultrastructural findings and reporting of new adnexal tumours these classifications have been modified by various authors.

   

Diagram of normal skin showing the skin appendages:

By  Dr. Sampurna Roy MD

 

Sebaceous Tumours

Ectopic Sebaceous Glands:

Fordyce's spot

Hamartomas and Hyperplasias:

Folliculosebaceous Cystic Hamartoma

Steatocystoma

Nevus Sebaceous of Jadassohn

Sebaceous Hyperplasia

Benign:

Sebaceous Adenoma

Sebaceoma

Malignant:

Sebaceous Carcinoma

Tumours with focal sebaceous differentiation:

Basal cell carcinoma (the term "basal cell carcinoma with sebaceous differentiation" should be used only for an otherwise conventional basal cell carcinoma with histological evidence  of sebaceous differentiation) ;  Squamous cell carcinoma ; Seborrheic keratosis.

 
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Hair Follicle Tumour

Hair Germ Differentiation:

Trichoepithelioma 

Desmoplastic Trichoepithelioma

Trichofolliculoma

Trichoblastoma

Cutaneous lymphadenoma
                           
Infundibular differentiation:

Trichoadenoma

Dilated Pore of Winer

Pilar Sheath Acanthoma

Tumour of Follicular Infundibulum

Outer root sheath differentiation:
   
                 
Trichilemmoma

Trichilemmal Carcinoma

Proliferating Trichilemmal Cyst (Pilar Tumour)

Matrical differentiation:
  
               
Pilomatrixoma and Pilomatrix Carcinoma

                            

 

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Sweat Gland Tumour

 

Cysts:

Hydrocystoma -Eccrine/Apocrine

Hamartomas

Eccrine/Apocrine naevus

Eccrine Angiomatous  Hamartoma

Porokeratotic eccrine ostial naevus

Benign Neoplasms:

Syringocystadenoma Papilliferum

Hidradenoma Papilliferum

Nipple Adenoma

Syringoma

Spiradenoma

Cylindroma

Chondroid Syringoma (benign mixed tumour)

Poroma

Hidradenoma

Apocrine adenoma

Papillary eccrine adenoma

Syringofibroadenoma

Malignant  Neoplasms

Low grade:

Microcystic adnexal carcinoma

Eccrine epithelioma

Adenoid cystic carcinoma

Mucinous carcinoma

Primary extramammary Pagetís disease

Intermediate grade:

Porocarcinoma

Digital papillary adenocarcinoma

High grade:

Hidradenocarcinoma

Apocrine adenocarcinoma

Eccrine ductal carcinoma

Spiradenocarcinoma

Malignant cylindroma


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