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 Classification of Soft Tissue Tumour

 Dr  Sampurna Roy   MD
The cutaneous appendages give rise to a wide range of tumours. This rare group of tumours is characterised by variable degrees of differentiation toward one or more skin appendages (Sweat gland- eccrine; apocrine; apoeccrine  ; Sebaceous glands and  Hair follicle). Various classifications have been proposed in the past.  In view of the new histochemical & ultrastructural findings and reporting of new adnexal tumours these classifications have been modified by various authors.

 
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  Adipocytic Tumours

Ectopic  Sebaceous Glands:

Fordyce's spot

Hamartomas and Hyperplasias:

Folliculosebaceous Cystic Hamartoma

Steatocystoma

Nevus Sebaceous of Jadassohn

Sebaceous Hyperplasia

Benign:

Sebaceous Adenoma

Sebaceoma

Malignant:

Sebaceous Carcinoma

Tumours with focal sebaceous differentiation:

Basal cell carcinoma (the term "basal cell carcinoma with sebaceous differentiation" should be used only for an otherwise conventional basal cell carcinoma with histological evidence of sebaceous differentiation) ; Squamous cell carcinoma ; Seborrheic keratosis.

 Visit:Adnexal Tumours of the eyelid

External Site: Images of normal skin adnexal structures : click

Normal skin appendages : click

Blue Histology: click

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  Adipocytic Tumours

Hair Germ Differentiation:

Trichoepithelioma 

Desmoplastic Trichoepithelioma

Trichofolliculoma

Trichoblastoma

Cutaneous lymphadenoma

                          
    
Infundibular differentiation:

Trichoadenoma

Dilated Pore of Winer

Pilar Sheath Acanthoma

Tumour of Follicular Infundibulum

Outer root sheath differentiation:
                    
Trichilemmoma

Trichilemmal Carcinoma

Proliferating Trichilemmal Cyst (Pilar Tumour)

Matrical differentiation:
                  
Pilomatrixoma and Pilomatrix Carcinoma

Follicular mesenchymal differentiation: (this is a rare group of tumours)

Trichodiscoma ; Neurofollicular hamartoma ; Fibrofolliculoma   ; Perifollicular fibroma

  Adipocytic Tumours

Cysts:

Hydrocystoma -Eccrine/Apocrine

Hamartomas:

Eccrine/Apocrine naevus

Eccrine Angiomatous Hamartoma

Porokeratotic eccrine ostial naevus

Benign Neoplasms:

Syringocystadenoma Papilliferum

Hidradenoma Papilliferum

Nipple Adenoma

Syringoma

Spiradenoma

Cylindroma

Chondroid Syringoma (benign mixed tumour)

Poroma

Hidradenoma

Apocrine adenoma

Papillary eccrine adenoma

Syringofibroadenoma

Malignant  Neoplasms

Low grade:

Microcystic adnexal carcinoma

Eccrine epithelioma

Adenoid cystic carcinoma

Mucinous carcinoma

Primary extramammary Paget’s disease

Intermediate grade:

Porocarcinoma

Digital papillary adenocarcinoma

High grade:

Hidradenocarcinoma

Apocrine adenocarcinoma

Eccrine ductal carcinoma

Spiradenocarcinoma

Malignant cylindroma