DermPath-India

     Site created by

 Dr Sampurna Roy MD

          

http://www.histopathology-india.net/dermpath.htm

                HISTOPATHOLOGY INDIA.COM

      Desmoplastic/Spindle cell
/Neurotropic Melanoma

          Dr. Sampurna Roy  MD

 
Web www.histopathology-india.net
      Gastrointestinal Stromal Tumour

          

http://www.histopathology-india.MelanocyticTumours.htm

May 2007
Surgical-Pathology.com

Histopathology-India.net  

Eye Pathology Online

Cardiac Path Online;

Pulmonary Pathology Online

Pathology Quiz Online;

Dermpath-India;

GI Path Online

Mesothelioma-Online;

Soft Tissue Pathology;

Infectious Disease Online;

INDEX: A-D ; INDEX: E-L ;INDEX: M-P ;INDEX: Q-Z ; FUNGAL DISEASE ; VIRAL DISEASE.

Melanocytic tumours
              
1. Acquired Melanocytic Naevus

Ancient Naevus
Halo naevus
Balloon cell naevus
Combined Naevus
Recurrent melanocytic naevus

                   
2. Spindle and epithelioid cell naevi

Spitz naevus
Pigmented spindle cell naevus

3. Blue naevi

Common blue naevus 
Cellular blue naevus


4. Dermal melanocytoses

Naevus of Ota

Naevus of Ito  
Mongolian spot  

5. Congenital melanocytic naevi                                              
6. Dysplastic melanocytic naevi

Pathology of the Eyelid

Inflammatory diseases of the Eyelid

Tumour and tumour-like lesions of the Eyelid

Adnexal Tumours of the eyelid

Epidermal tumours of the Eyelid

Mesenchymal Tumours of the Eyelid

Melanocytic tumours of the Eyelid

Cutaneous Deposits

Calcinosis Cutis

Cutaneous Ossification (Osteoma Cutis)

Cartilaginous lesions of skin

Lipoid Proteinosis

Gout

Silicone granulomas

 
                
Superficial spreading melanoma may develop in any part of the body and at any age.

It is commonly noted on the trunk and lower extremities.

Macroscopically, the  lesion has a variegated colour and an expanding  irregular margin . Dermatlas Image link

Histologically , the lesion is characterized by proliferation of atypical melanocytes at all levels in the epidermis. The tumour cells are present singly and in nests. There is evidence of pagetoid spread in the epidermis (buckshot spread).  The tumour cells may be epithelioid, spindle or nevus cell-like in appearance. The superficial adnexal epithelium may be involved.

The differential diagnosis includes extramammary and mammary Paget's disease, squamous carcinoma with pagetoid pattern in the epidermis . S100 and HMB45 stains are positive in melanoma.

Verrucous melanoma is a variant of superficial spreading melanoma and is characterized by prominent epidermal hyperplasia and elongation of rete ridges.

Pigmented Bowen's Disease of the FingerMimicking Malignant Melanoma. Arch Iran Med. 2007 Apr;10(2):225-7.
                         Image Link(Dr Weems)     

                      

Abstracts:

Molecular cytogenetic characterization of a novel cell line established from a superficial spreading melanoma.Front Biosci. 2006 May 1;11:1844-53.

Sun exposure, phenotypic characteristics, and cutaneous malignant melanoma. An analysis according to different clinico-pathological variants and anatomic locations (Italy).Cancer Causes Control. 2005 Oct;16(8):893-9.

Only superficial spreading melanoma is causing the melanoma epidemics?Eur J Epidemiol. 2004;19(1):91-2.

Invasive superficial spreading melanomas arising from clinically normal skin.J Am Acad Dermatol. 2004 Sep;51(3):466-70.

Superficial spreading melanoma arising in a longstanding melanocytic nevus on the sole.J Dermatol. 1998 May;25(5):337-40.

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Pulmonary Pathology Online

Examination of pulmonary and pleural biopsies ; Percutaneous Needle and Trucut Biopsy Specimen  ; Bronchial Biopsy Specimen  ;Transbronchial Biopsy Specimen  ; Transbronchial biopsy in lung transplant recipients  ; Open lung biopsy  ; Lobectomy and pneumectomy specimen ; Histopathological reporting of pulmonary parenchymal biopsies ;Useful chromatic and immuno-stains in pulmonary pathology ;Congenital Cystic Adenomatoid Malformation ; Chondroid Hamartoma ; Acute Respiratory Distress Syndrome ; Neonatal Respiratory Distress Syndrome ; Complications of Neonatal Respiratory Distress Syndrome Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis) ; Chronic Obstructive Pulmonary Disease ;Bronchial Asthma ; Bronchiectasis ; Chronic Bronchitis  ; Emphysema ;Bronchiolitis ; Lipid Pneumonia (Paraffinoma) ; Pulmonary Alveolar Proteinosis ;Pulmonary Thromboembolism ; Other forms of  Pulmonary Embolism ; Pulmonary Infarction ; Pulmonary Hypertension ; Pulmonary Collapse (Atelectasis) and Pneumothorax ; Pulmonary Edema ; Pulmonary Hemorrhage (Eg. Goodpasture's Syndrome) ; Sarcoidosis ; Lymphangioleiomyomatosis ; Localized Fibrous Tumour of the Pleura ; Pulmonary Lymphoproliferative Disease ; Lymphomatoid Granulomatosis ;Post-Transplant Lymphoproliferative Disease ;Biphasic Epithelial/ Mesenchymal Lung Tumours ;Pulmonary Carcinosarcoma ; Pulmonary Blastoma ;Large Cell Neuroendocrine tumour ;

 
Web www.histopathology-india.net
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Pigmented melanocytic lesions causing diagnostic problems

Prognostic parameters of melanoma

Lentigo maligna melanoma

Superficial spreading melanoma

Nodular melanoma

Acral lentiginous melanoma

Desmoplastic /Spindle cell /
Neurotropic melanoma

Naevoid melanoma

Balloon cell melanoma

Myxoid Tumours of Soft Tissue

Classification of Soft Tissue Tumour

Lipomatous tumours

Neural tumours

Vascular tumours

Myogenic tumours

Fibroblastic/Myofibroblastic tumours

Myofibroblastic tumours

Fibrohistiocytic tumours

ChondroOsseous tumours

Soft TissueTumours of Uncertain Differentiation               

Notochordal Tumour - Chordoma

Extra-adrenal Paraganglioma