Classification of Soft Tissue Tumour

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Benign:

Lipoma

Lipomatosis

Lipomatosis of nerve

Lipoblastoma / Lipoblastomatosis

Angiolipoma

Myolipoma

Chondroid lipoma

Extrarenal angiomyolipoma

Extra-adrenal myelolipoma

Spindle cell/

Pleomorphic lipoma

Hibernoma

Intermediate (locally aggressive):

Atypical lipomatous tumour/

Well differentiated liposarcoma

Malignant:

Dedifferentiated liposarcoma

Myxoid liposarcoma

Round cell liposarcoma

Pleomorphic liposarcoma

Mixed-type liposarcoma

Liposarcoma, not otherwise specified.

Benign:

Angioleiomyoma

Deep leiomyoma

Genital leiomyoma

Malignant:

Leiomyosarcoma (excluding skin)

Benign:

Rhabdomyoma

adult type ; fetal type ; genital type

Malignant:

Embryonal rhabdomyosarcoma

(incl. spindle cell, botryoid,

anaplastic)

Alveolar rhabdomyosarcoma

(incl. solid, anaplastic)

Pleomorphic rhabdomyosarcoma

Soft tissue chondroma

Mesenchymal chondrosarcoma

Extraskeletal osteosarcoma

Benign:

Nodular fasciitis

Proliferative fasciitis

Proliferative myositis

Myositis ossificans

   fibro-osseous pseudotumour of digits

Ischaemic fasciitis

Elastofibroma

Fibrous hamartoma of infancy

Myofibroma / Myofibromatosis

Fibromatosis colli

Juvenile hyaline fibromatosis

Inclusion body fibromatosis

Fibroma of tendon sheath

Desmoplastic fibroblastoma

Mammary-type myofibroblastoma

Calcifying aponeurotic fibroma

Angiomyofibroblastoma

Cellular angiofibroma

Nuchal-type fibroma

Gardner fibroma

Calcifying fibrous tumour

Giant cell angiofibroma

Intermediate (locally aggressive)

Superficial fibromatoses (palmar/ plantar)

Desmoid-type fibromatoses

Lipofibromatosis

Intermediate (rarely metastasizing):

Solitary fibrous tumour and haemangiopericytoma

(incl. lipomatous haemangiopericytoma)

Inflammatory myofibroblastic tumour

Low-grade myofibroblastic sarcoma

Myxoinflammatory fibroblastic sarcoma

Infantile fibrosarcoma

Malignant:

Adult fibrosarcoma

Myxofibrosarcoma

Low-grade fibromyxoid sarcoma

      hyalinizing spindle cell tumour

Sclerosing epithelioid fibrosarcoma



Benign:

Giant cell tumour of tendon sheath

Diffuse-type giant cell tumour

Deep benign fibrous histiocytoma

Intermediate(rarely metastasizing):

Plexiform fibrohistiocytic tumour

Giant cell tumour of soft tissues

Malignant:

Pleomorphic ‘MFH’ / Undifferentiated pleomorphic sarcoma

Giant cell ‘MFH’ / Undifferentiated pleomorphic sarcoma with giant cells

Benign:

Haemangiomas of subcut/deep soft tissue: capillary ; cavernous ; arteriovenous ; venous ; intramuscular ; synovial.

Epithelioid haemangioma

Angiomatosis

Lymphangioma

Intermediate (locally aggressive):

Kaposiform haemangioendothelioma

Intermediate (rarely metastasizing):

Retiform haemangioendothelioma

Papillary intralymphatic angioendothelioma

Composite haemangioendothelioma

Kaposi sarcoma

Malignant:

Epithelioid haemangioendothelioma

Angiosarcoma of soft tissue

Glomus tumour (and variants)

Malignant glomus tumour

Myopericytoma

Benign:

Intramuscular myxoma (incl. cellular variant)

Juxta-articular myxoma

Deep (‘aggressive’) angiomyxoma

Pleomorphic hyalinizing angiectatic tumour

Ectopic hamartomatous thymoma

Intermediate (rarely metastasizing):

Angiomatoid fibrous histiocytoma

Ossifying fibromyxoid tumour (incl. atypical / malignant)

Mixed tumour/ Myoepithelioma/ Parachordoma

Malignant:

Synovial sarcoma

Epithelioid sarcoma

Alveolar soft part sarcoma

Clear cell sarcoma of soft tissue

Extraskeletal myxoid chondrosarcoma ("chordoid" type)

PNET / Extraskeletal Ewing tumour

           pPNET

           Extraskeletal Ewing tumour

Desmoplastic small round cell tumour

Extra-renal rhabdoid tumour

Malignant mesenchymoma

Neoplasms with perivascular epithelioid cell differentiation (PEComa) ;

        clear cell myomelanocytic tumour

Intimal sarcoma

Soft Tissue Pathology;

Myxoid Tumours of Soft Tissue ; Classification of Soft Tissue Tumour; Gross examination of soft tissue specimen ; A practical approach to histopathological reporting of soft tissue tumours ; Grading of soft tissue tumours ; Lipomatous tumours ;Neural tumours ; Myogenic tumours ;Vascular tumours ;Fibroblastic/Myofibroblastic tumours ; Myofibroblastic tumours ; Fibrohistiocytic tumours ; ChondroOsseous tumours ; Soft TissueTumours of Uncertain Differentiation ; Notochordal Tumour -Chordoma ;Extra-adrenal Paraganglioma ; Gastrointestinal Stromal Tumour ;