http://www.histopathology-india.net/SebTum.htm

   

      Site created by

  Dr Sampurna Roy MD

http://www.histopathology-india.net/dermpath.htm

Sebaceous adenoma is most closely associated with the Muir-Torre syndrome. Sebaceous tumours

Clinical presentation:  May be solitary or multiple ;  Yellow-pink circumscribed papule/nodule ( 0.5 cm in diameter) ; may ulcerate or bleed.

Site:  Located on the head and neck region. Rarely located on the buccal mucosa.

Microscopic features:

Histologically,  sebaceous adenoma is a multilobulated tumour sharply demarcated from the surrounding tissue.

Two types of cells are present in the lobules.
The large mature sebaceous cells (sebocytes) are present at the centre. Smaller, undifferentiated basaloid cells in the periphery

The cellular lobules contain ductal strutures with holocrine secretion.

Sometimes lobules contain cystic spaces in the centre due to disintegration of mature sebaceous cells. Cystic sebaceous tumours are regarded as a marker of Muir-Torre syndrome.

           Image Link (Dr Weems)
 

Sebaceous adenoma of oral cavity: report of case and comparative proliferation study with sebaceous gland hyperplasia and Fordyce's granules.Oral Dis. 2003;9(6):323-7.