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Dermpath-India

Benign Sweat Gland Tumours

Dr Sampurna Roy MD   

 

                                                                                                                      

 

 

Adnexal tumours can differentiate towards the ductal and or/glandular portion of the eccrine or apocrine glands. 

It is not possible to distinguish on histological ground between the ductal portion of eccrine and apocrine glands.

Traditionally most tumours have been considered to show eccrine ductal differentiation. 

Ackerman and colleagues have reclassified many of the traditional eccrine tumours to apocrine categories.

Extensive sampling may reveal foci of decapitation secretion in tumours classically regarded as eccrine.

Some of the glandular tumours reveal at least small foci of sebaceous or follicular differentiation.

Sweat gland and ductal differentiation: Characterized by formation of glandular/duct structures and presence of intracytoplasmic glandular lumina.

True ducts and intracytoplasmic lumina can be highlighted by their diastase-resistant periodic acid-Schiff (PAS), epithelial membrane antigen (EMA) and carcinoembryonic antigen positivity. 

Currently the diagnostic utility of immunohistochemisty is doubtful.

Apocrine differentiation:  Characterized by decapitation secretion - Ductal changes with apocrine snouting.

 

Classification:

Cysts:

Hydrocystoma -Eccrine/Apocrine


Hamartomas:

Eccrine/Apocrine naevus

Eccrine Angiomatous Hamartoma

Porokeratotic eccrine ostial naevus


Benign Neoplasms:

Syringocystadenoma Papilliferum


Hidradenoma Papilliferum


Nipple Adenoma (florid papillomatosis of the nipple ducts)


Syringoma


Spiradenoma


Cylindroma


Chondroid Syringoma


Poroma


Hidradenoma


Apocrine adenoma/cystadenoma


Papillary eccrine adenoma


Syringofibroadenoma

 

 

 

 


 

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