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Tumour of the Follicular

Infundibulum 

Dr Sampurna Roy MD

Dermpath-India

Site created by

Dr Sampurna Roy MD

       

http://www. histopathology-india.net/dermpath.htm

March 2014
Benign sweat gland tumours

Cysts:

Hydrocystoma -Eccrine/Apocrine

Hamartomas:

Eccrine/Apocrine naevus

Eccrine  Angiomatous Hamartoma

Porokeratotic  eccrine ostial naevus

Benign Neoplasms:

Syringo cystadenoma Papilliferum

Hidradenoma Papilliferum

Nipple Adenoma

Syringoma

Spiradenoma

Cylindroma

Chondroid Syringoma (benign mixed tumour)

Poroma

Hidradenoma

Apocrine adenoma

Papillary eccrine adenoma

Syringo fibroadenoma

Malignant sweat gland tumour 

Low grade:

Microcystic adnexal carcinoma

Eccrine epithelioma

Adenoid cystic carcinoma

Mucinous  carcinoma

Primary extramammary Pagetís disease

Intermediate grade:

Porocarcinoma

Digital papillary adenocarcinoma

High grade:

Hidradeno carcinoma

Apocrine adenocarcinoma

Eccrine ductal carcinoma

Spiradeno carcinoma

Malignant cylindroma

Sebaceous tumours

Fordyce's Spots

Steatocystoma

Nevus Sebaceous

Folliculosebaceous Cystic Hamartoma

Sebaceous Hyperplasia

Sebaceoma

Sebaceous Adenoma

Sebaceous Carcinoma

                    
Tumour of the follicular infundibulum (TFI) is a simple follicular acanthoma with characteristic histopathologic features.

Classified as:

(1) solitary tumours,

(2) eruptive tumours,

(3) TFI - associated with other lesions of Cowden's disease,

(4) TFI- associated with a single tumour such as nevus sebaceus, and

(5) TFI-like epidermal changes.

Clinically presents as a small asymptomatic, smooth or slightly keratotic papule or plaque.

Sites:  Head and neck or upper chest.

Microscopic features:

   

Symmetrical tumour with plate-like growth pattern of the squamous cell (similar to isthmic or outer root sheath epithelium) parallel to the surface epithelium ;

Multiple attachments to the epidermis ;

Basal cell palisade ;

Acanthotic epithelium eosinophilic and pale staining than the overlying epidermis ;

Small ducts and microcavities with keratin in the lesion; PAS- positive basement membrane.

Differential diagnosis: 

Inverted follicular keratoses ; 

Trichilemmomas  ; 

Plaque-like seborrheic keratosis ;   

Superficial basal cell carcinoma; 

Multiple infundibular tumors of the head and neck.  

                            

Further reading:

Solitary and multiple tumors of follicular infundibulum: a review of 168 cases with emphasis on staining patterns and clinical variants.

Eruptive tumors of the follicular infundibulum presenting as hypopigmented macules on the buttocks of two Black African males.

A case of tumor of the follicular infundibulum with sebaceous differentiation.

Tumor of follicular infundibulum is Basal cell carcinoma.

Tumor of the follicular infundibulum: an epidermal reaction pattern?

[Vitiligoid hypopigmented macules and tumor of the follicular infundibulum].

Multiple tumors of the follicular infundibulum. Dermatol Surg. 2004 Sep;30(9):1246-8.

Coexistence of tumor of the follicular infundibulum with an unusual trichilemmal tumor.Am J Dermatopathol. 2002 Oct;24(5):406-8.

Clinicopathological report Periocular tumour of the follicular infundibulum.Clin Experiment Ophthalmol. 2001;29(2):100-1.

Tumor of the follicular infundibulum with sebaceous differentiation.J Cutan Pathol. 2001 Jul;28(6):314-7.

Tumor of the follicular infundibulum. Study of determining follicular differentiation.Pathologe. 1996 Nov;17(6):440-5

Multiple tumors of follicular infundibulum with sweat duct differentiation.J Cutan Pathol. 1995 Jun;22(3):281-7.

Tumor of the follicular infundibulum: a clinicopathologic study.: J Am Acad Dermatol. 1995 Dec;33(6):979-84.

A tumor of follicular infundibulum. Arch Dermatol 1961;83:924

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Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)

 

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