Skin Appendage Tmour

      

http://www.histopathology-india.net/HFoTu.htm

                      HISTOPATHOLOGY INDIA.COM

      Microcystic Adnexal Carcinoma 

         Dr  Sampurna Roy  MD

 
Web www.histopathology-india.net
     DermPath-India

     Site created by

  Dr Sampurna Roy MD

          

http://www.histopathology-india.net/dermpath.htm

June 2007

Benign sweat gland tumours

Cysts:

Hydrocystoma -Eccrine/Apocrine

Hamartomas:

Eccrine/Apocrine naevus

Eccrine Angiomatous Hamartoma

Porokeratotic eccrine ostial naevus

Benign Neoplasms:

Syringocystadenoma Papilliferum

Hidradenoma Papilliferum

Nipple Adenoma

Syringoma

Spiradenoma

Cylindroma

Chondroid Syringoma (benign mixed tumour)

Poroma

Hidradenoma

Apocrine adenoma

Papillary eccrine adenoma

Syringofibroadenoma

Malignant sweat gland tumour 

Low grade:

Microcystic adnexal carcinoma

Eccrine epithelioma

Adenoid cystic carcinoma

Mucinous carcinoma

Primary extramammary Paget’s disease

Intermediate grade:

Porocarcinoma

Digital papillary adenocarcinoma

High grade:

Hidradenocarcinoma

Apocrine adenocarcinoma

Eccrine ductal carcinoma

Spiradenocarcinoma

Malignant cylindroma

                    
Tumour of the follicular infundibulum (TFI)  is a simple follicular acanthoma with characteristic histopathologic features.

Classified as: (1) solitary tumours, (2) eruptive tumours, (3) TFI - associated with other lesions of Cowden's disease, (4) TFI- associated with a single tumour such as nevus sebaceus, and (5) TFI-like epidermal changes.

Clinically presents as a small asymptomatic, smooth or slightly keratotic papule or plaque.

Sites:  Head and neck or upper chest.

Microscopic features:

Symmetrical tumour with plate-like growth pattern  of the squamous cells ( similar to isthmic or outer root sheath epithelium) parallel to the surface epithelium ; Multiple attachments to the epidermis ; Basal cell palisade ; Acanthotic epithelium eosinophilic and pale staining than the overlying epidermis ; Small ducts and microcavities with keratin in the lesion; PAS- positive basement membrane.

Differential diagnosis:  Inverted follicular keratoses ;  trichilemmomas  ;  Plaque-like seborrheic keratosis ;    Superficial basal cell carcinoma;  Multiple infundibular tumors of the head and neck.

         Image link ( W.Weems)  ;   Image link

             

 
Web www.histopathology-india.net

Abstracts:

Multiple tumors of the follicular infundibulum.Dermatol Surg. 2004 Sep;30(9):1246-8.

Coexistence of tumor of the follicular infundibulum with an unusual trichilemmal tumor.Am J Dermatopathol. 2002 Oct;24(5):406-8.

Clinicopathological report Periocular tumour of the follicular infundibulum.Clin Experiment Ophthalmol. 2001;29(2):100-1.

Tumor of the follicular infundibulum with sebaceous differentiation.J Cutan Pathol. 2001 Jul;28(6):314-7.

Tumor of the follicular infundibulum. Study of determining follicular differentiation.Pathologe. 1996 Nov;17(6):440-5

Multiple tumors of follicular infundibulum with sweat duct differentiation.J Cutan Pathol. 1995 Jun;22(3):281-7.

Tumor of the follicular infundibulum: a clinicopathologic study.: J Am Acad Dermatol. 1995 Dec;33(6):979-84.

A tumor of follicular infundibulum. Arch Dermatol 1961;83:924

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Tumours of the Hair Follicle

Hair Germ Differentiation:

Trichoepithelioma 

Desmoplastic Trichoepithelioma

Trichofolliculoma

Trichoblastoma

Cutaneous lymphadenoma

                          
    
Infundibular differentiation:

Trichoadenoma

Dilated Pore of Winer

Pilar Sheath Acanthoma

Tumour of Follicular Infundibulum

Outer root sheath differentiation:
                    
Trichilemmoma

Trichilemmal Carcinoma

Proliferating Trichilemmal Cyst (Pilar Tumour)

Matrical differentiation:
                  
Pilomatrixoma and Pilomatrix Carcinoma