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            Fibrous Hamartoma of Infancy

 
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-  Stenosis :   Image Link  The aetiology of this is due to three causes - Post-inflammatory, endocarditis, carcinoid and very rarely congenital.

- Incompetence: Image Link

1. Functional  

2. Rheumatic :  Rheumatic disease affecting the tricuspid valve almost always affects the mitral and aortic valves as well. The valve leaflets are diffusely fibrosed with commissural fusion but calcification is rare. The chordae tendineae may be thickened and shortened but it is usually not as extensive as the mitral valve.

3. Endocarditis

4. Carcinoid Heart Disease

5. Floppy Valve Disease

6. Congenital (Ebstein's Anomaly)

7. Trauma

8. Endomyocardial fibrosis

9. Papillary muscle infarction

Histology : Often valves have a limited and common response to disease so that histology of valve tissue is not very useful in the majority of cases. Fibrosis with calcification are the most usual responses.

In cases in which histology of a valve may be helpful, the leaflets are sectioned together with a portion of the adjacent chambers and / or vessel walls.

For example, the posterior leaflet of the mitral valve is sectioned including a portion of left atrium and left ventricular free wall : the anterior leaflet includes ventricular septum and non-coronary cusp of the aortic valve.  In cases of rheumatic heart disease sections of the atrial appendages may be included for histological examination because the incidence of Aschoff bodies is highest in these structures.

          

A practical approach to examination of cardiac valves

Cardiac Valve Disease

 
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May 2007
      
FUNCTIONAL ANATOMY OF THE HEART

ANATOMY OF THE ATRIUM

ANATOMY OF THE VENTRICLE

ANATOMY OF THE CORONARY ARTERIES

AUTOPSY EXAM. OF CORONARY ARTERIES

EXAMINATION  OF CARDIAC  VALVES

CARDIAC  VALVE  DISEASE

MITRAL  VALVE LESIONS

PULMONARY VALVE DISEASE

TRICUSPID VALVE DISEASE

CARDIOMYOPATHY

CONGESTIVE HEART FAILURE

congenital heart disease

Ischemic heart disease    

Angina pectoris

Myocardial infarction                
 
hypertensive heart disease  
 
RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE
 
PATHOLOGY OF ASCHOFF BODIES OR NODULES
 
myocardiTIS
 
GIANT CELL MYOCARDITIS    

pericardial disease  

INFECTIVE ENDOCARDITIS

CARDIAC HEMOCHROMATOSIS

CARDIAC AMYLOIDOSIS

HISTOPATHOLOGY REPORTING OF PERICARDIAL SPECIMEN

HEART TRANSPLANTS - PATHOLOGICAL EXAMINATION

ENDOMYOCARDIAL BIOPSY-(ALLOGRAFT REJECTION):

ISHLT SYSTEM FOR GRADING REJECTION

POST-OPERATIVE CARDIAC PATHOLOGY

PERIOPERATIVE CARDIAC PATHOLOGY

PRIMARY TUMOURS OF THE HEART

REPORTING OF CARDIAC TUMOURS

CARDIAC MYXOMA

CARDIAC RHABDOMYOMA

PAPILLARY FIBROELASTOMA

CARDIAC FIBROMA

CARDIAC LIPOMA

CARDIAC HEMANGIOMA

CARDIAC TERATOMA

MESOTHELIOMA OF ATRIOVENTRICULAR NODE

PURKINJE CELL TUMOUR

CARDIAC PARAGANGLIOMA

MALIGNANT TUMOURS OF THE HEART

CARDIAC LYMPHOMA