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Soft Tissue Pathology Online

Soft Tissue Tumours of Uncertain Differentiation

Dr Sampurna Roy MD          

 

                                                                                                                      

 

Tumors of uncertain differentiation include benign and malignant tumours with distinct  features but uncertain lineage,

A number of these tumours show genetic aberrations.

Translocation-associated soft tissue tumors and sarcomas are included in this category.

Cellular component of these tumours  do not belong to a normal cell type and have distinctive patterns of gene expression.

Translocation associated sarcomas often do not show nuclear pleomorphism. These tumours are considered aggressive high grade sarcomas.

In this list of tumours I have included both dermal and soft tissue tumours of uncertain differentiation:

 

             Superficial Acral Fibromyxoma

 

 

             Digital Mucous (Myxoid) Cyst

 

 

             Non Neural Granular cell tumour

 

 

                                       Hemosiderotic Fibrolipomatous tumour

            

 

              Angiomatoid Fibrous Histiocytoma

 

 

              Aggressive Angiomyxoma

 

 

              Angiomyofibroblastoma

 

 

              Intramuscular Myxoma

 

 

              Ossifying fibromyxoid tumour

 

 

              Synovial Sarcoma

 

 

               Alveolar Soft Part Sarcoma

 

 

               Epithelioid Sarcoma

 

 

               Clear cell sarcoma

 

 

              Extraskeletal Ewing's Sarcoma / PNET

 

 

              Desmoplastic small round cell tumour

 

 

 

             Ectopic hamartomatous thymoma

 

 

             Extra-renal rhabdoid tumour

 

 

 

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)


 

 

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