Dermpath-India: Histopathology Image of Verruca Vulgaris1

Histopathology Image of

Verruca Vulgaris 1

[The appearance of pathognostic inclusion bodies in verruca vulgaris (author's transl)]. Zentralbl Allg Pathol. 1978; 122(3):214-9.

Pathognostic inclusion bodies develop in the nucleus. They frequently occur in the upper layers of the pathologically changed stratum spinosum. They are stained in an amphophilic or basophilic manner. Their structure is a nearly homogenous, finely grained or plaquelike one. The inclusion bodies contain masses of human wart viruses in a cristalline-like arrangement or are irregularily distributed. Feulgen staining is positive. Different pictures of inclusion bodies are demonstrated in paraffin sections. The knowledge of structural variants is very helpful in biopsy diagnosis of veruca vulgaris.

Ultrastructural studies of intraoral verruca vulgaris.Oral Surg Oral Med Oral Pathol. 1979 Jan;47(1) :58-62.

The literature offers conflicting views regarding the existence of verruca vulgaris in the oral cavity. In an attempt to clarify this issue, a series of ten oral lesions which had been diagnosed as verruca vulgaris and ten oral lesions diagnosed as squamous-cell papilloma were examined ultrastructurally. Six of the lesions diagnosed as verruca vulgaris contained the characteristic intranuclear viral particles which are normally found in that lesion. None of the lesions diagnosed as squamous-cell papilloma exhibited this type of intranuclear viral inclusions.

Verruca vulgaris