DermPath-India

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            Myxoid Tumours of Soft Tissue

        Dr Sampurna Roy MD

 
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December  2009 
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Case (Image) Link: click here

Warty dyskeratoma is a rare, benign, epithelial tumour.

According to some authors, majority of these lesions display overall histopathologic features consistent with a follicular adnexal neoplasm. On the basis of this finding, the term follicular dyskeratoma has been suggested.

These are rare usually solitary lesions with an umbilicated center.

Age:  Usually occur in middle aged or elderly patients.

Site:   Located on the head and neck region.

Microscopic features: Image Link1 ; Image Link2 ; Image Link3 .

Histology reveals cup shaped, well circumsribed lesion characterized by suprabasilar clefting , acantholysis, dyskeratosis and keratinous plug. Villi protrude into the lacuna.  Villi are dermal papillae lined by basal cells and contain inflammatory cells and dilated blood vessels.

 IMAGE LINK

Note:   Acantholytic dyskeratosis is a histopathologic pattern defined by a hyperkeratotic and parakeratotic epidermis with intraepidermal clefts containing acantholytic and dyskeratotic keratinocytes. These features may be present in Warty dyskeratoma ; Darier disease ; Grover disease ; Hailey Hailey disease ; Acantholytic and dyskeratotic epidermal nevus, Focal acantholytic dyskeratosis ; Acantholytic solar keratosis ; Vulval and anal acantholytic dyskeratosis.

                    

 Abstracts:

Warty dyskeratoma or "follicular dykeratoma": a clinicopathologic features of a new entity.Tunis Med. 2005 Apr;83(4):227-9.

Warty dyskeratoma--"follicular dyskeratoma": analysis of clinicopathologic features of a distinctive follicular adnexal neoplasm.J Am Acad Dermatol. 2002 Sep;47(3):423-8.

Multiple warty dyskeratomas of the scalp .Clin Exp Dermatol.1997 ;22(4):189-91.

Focal subungual warty dyskeratoma.Dermatology. 1997;195(3):278-80.

Warty dyskeratoma with multiple lesions. J Dermatol. 1993 Jun;20(6):374-7.

Warty dyskeratoma of the oral mucosa. Correlated light and electron microscopic study.Oral Surg Oral Med Oral Pathol. 1984 Aug;58(2):176-83.

Focal oral warty dyskeratoma.Int J Dermatol. 1984 Mar;23(2):123-30.

Warty dyskeratoma of the vulva.Int J Gynecol Pathol. 1983;2(3):286-93.

                        

 

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