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Pulmonary Pathology Online

Biphasic Epithelial /Mesenchymal Tumours of Lung

Dr Sampurna Roy MD




Biphasic epithelial/mesenchymal tumours are characterized by the admixture of epithelial and mesenchymal elements in the same tumour.


Mixed tumours of the lung include carcinosarcomas, pulmonary blastomas, which probably represent a distinctive subgroup of carcinoma, and teratomas, all of which are rare.


There are no true benign mixed tumour.


The so-called mixed tumours of salivary gland type, which may arise in bronchial glands, derives its cartilaginous component from myoepithelial cells and is more properly called a pleomorphic adenoma, whilst the many epithelial clefts that characterize the common so-called chondroid hamartoma are mere (non-neoplastic) inclusions.


Carcinosarcomas and blastomas are now regarded as carcinoma showing connective tissue differentiation and are now classified as carcinomas.


Biphasic epithelial/mesenchymal tumours represent less than 1% of all primary malignancies.

Pulmonary Carcinosarcoma

Pulmonary Blastoma

Further reading:

Mixed malignant tumour of the lung.

Malignant mixed epithelial/mesenchymal neoplasms of the lung.

The clinical analysis and review of literature of pulmonary carcinosarcoma and blastoma




Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)







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