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Chlamydial Infections in Human

Dr Sampurna Roy MD




Chlamydiae are obligate intracellular gram-negative bacteria that have a unique two-stage cycle.

i) The infectious and nonreplicating "elementary body", representing the extracellular stage, is a 0.2- to 0.4 micrometer sphere that has a rigid cell envelope and is metabolically inactive.

ii) The intracytoplasmic second stage, the reticulate body, is larger - 0.7 to 1.0 micrometer in diameter- and metabolically active, and multiplies by binary fission.

Chlamydial infections are widespread among birds and mammals, and perhaps 20% of the human population is infected.



Human diseases caused by chlamydiae can be divided into two types:

(1) Chlamydial agents transmitted by direct  contact (Chlamydia trachomatis, genital and ocular infections,  and

(2) Chlamydial agents that are transmitted by the respiratory route (Chlamydia psittaci and Chlamydia pneumoniae).

Chlamydial diseases in humans include:

Chlamydial Conjunctivitis (Inclusion Conjunctivitis) ;

Trachoma  ;

Chlamydial Infection of the Genital Tract ;

Psittacosis (Ornithosis, Parrot Fever) ;

Lymphogranuloma Venereum





Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)






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