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Pathology of Chondroblastoma of Temporal Bone

 

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Chondroblastoma is a rare benign bone tumour. It commonly affects the epiphysis of long bones during the second and third decades of life.   

Temporal bone chondroblastoma is a rare primary bone tumor that affects the floor of the middle cranial fossa.  

The tumours of the temporal bone show a great variety in their incidence. Tumours like the acoustic neurinoma or the paraganglioma are comparatively common in this location, but chondroblastoma is absolutely rare.

Clinically, it occurs as a mass in the postero-superior region of the ear canal and is accompanied by hearing loss. 

Histologically, this tumour is composed of round or polygonal chondroblasts and scattered osteoclast-like giant cells. Some cells show oval or grooved nuclei. Intercelluar calcification and hemorrhagic components are also observed in the tumour. Tumour cells are strongly positive for S-100 protein. 

Many reports describe giant cell tumor can be differentiated by immunohistochemical demonstration of S100 protein.

Diagnostic radiology, including computed tomography and/or magnetic resonance imaging, as well as immunohistochemical staining with S-100 protein may assist in making the diagnosis.

Treatment is complete surgical excision with preservation of vital neurovascular structures.

 

Further reading

Chondroblastoma of the temporal bone: consistent middle fossa involvement.

Chondroblastoma of the temporal bone.

Surgical treatment of temporal bone chondroblastoma.

Chondroblastoma of the temporal bone involving the temporomandibular joint, mandibular condyle, and middle cranial fossa: case report and review of the literature.

Temporal bone chondroblastomas.

Chondroblastoma of the temporal base with high mitotic activity.

Chondroblastoma of the temporal bone: a case report

Chondroblastoma of the temporal bone.

Chondroblastoma of the temporal bone: a clinicopathologic study of five cases.

Temporal bone chondroblastoma: big and small.

Chondroblastoma of the temporal bone. Case report and literature review.

Chondroblastoma of the temporal bone--report of a case and a review of the literature of 54 cases.

Chondroblastoma of temporal bone: unusual histologic features.

 

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Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)


 

 

 

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