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Pathology of Angiolymphoid Hyperplasia with Eosinophilia of the External Ear

Dr Sampurna Roy MD





Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare condition that demonstrates dermal or subcutaneous proliferation of endothelial cells associated with an inflammatory cell infiltrate and may occur in and around the ear (auricle and external canal).

The lesion is characterized by single or multiple smooth-top papules or plaques of varying colour.

The patient complains of pruritis and bleeding after scratching.

Microscopic features:  ALHE consists of anomalous vascular proliferations and varying degrees of nodular and diffuse lymphocytic infiltrates with eosinophils. 

Visit: Angiolymphoid Hyperplasia with Eosinophilia of Ear

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Differential diagnosis: Hemangioma and angiosarcoma.


Further reading:

Angiolymphoid hyperplasia with eosinophilia of the auricle: progression of histopathological changes.

Angiolymphoid hyperplasia with eosinophilia associated to a squamous cell carcinoma of the ear.

Pathological lesions of the external auditory meatus: a review.

Angiolymphoid hyperplasia with eosinophilia of the external ear (Kimura's disease).

Angiolymphoid hyperplasia with eosinophilia of the external ear canal.

Angiolymphoid hyperplasia with eosinophilia involving the external auditory canal.



Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)






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