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Pathology of Metastatic Tumours of Temporal Bone

Dr Sampurna Roy MD


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Metastatic carcinoma of the temporal bone is rare and often not recognized because it can be either asymptomatic or overshadowed by other metastases late in the disease course.

The commonest site of involvement in the temporal bone is the petrous apex followed by the tegmen tympani, mastoid bone and internal auditory canal.

Hearing loss is the most common otologic symptom.

Most common sites of origin are breast, lung, pharynx, kidney, stomach, larynx, thyroid and prostate. 

4 invasion modes include:

i)  Direct extension from head and neck tumours;

ii)  Hematological dissemination;

iii) Diffuse leptomeningeal carcinomatosis , and

iv) Direct extension of tumours from the intracranium.

Further reading

Comparison of duration of deafness and tumour invasion to the inner ear from metastatic tumours of the internal auditory canal: human temporal bone pathology.

Metastatic carcinoma of the temporal bone.

Metastases to temporal bones from primary nonsystemic malignant neoplasms.

Histopathology of metastatic temporal bone tumors.

Metastatic tumors in the temporal bone--a pathophysiologic study.

Metastatic tumours of the temporal bone. A histopathological report.

Secondary malignant tumors of the temporal bone. A histopathologic study and review of the world literature.

Secondary tumor of the temporal bone with internal auditory meatus involvement--histopathological study.


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Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)







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