is a chronic-inflammatory lesion that is most commonly iatrogenic of
It is caused by the implantation during surgery of mineral oil- or petroleum-based products into various tissues.
The condition results from the action of lipid substances on extravasated erythrocytes.
Histologically, ear biopsy may show cystic tissue spaces lined by histiocytes and foreign-body giant cells in a fibrous stroma.
In the tissue spaces, scattered debris and sac-like structures containing round spherules of aggregated erythrocytes are found. In addition, erosion of adjacent bone matrix may be seen.
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