Custom Search

           

Pathology of Erythema Chronicum Migrans

Dr Sampurna Roy MD


   
Erythema chronicum migrans is a skin lesion of the tick borne spirochetosis, Lyme disease.

The annular lesion, (measures 5-20 cm in diameter) develops within 3 months of the tick bite.

Lesions are multiple in some cases.

Secondary erythema migrans result from hematogenous spread of the organism.

The organism disappear from the lesion after treatment with antibiotics (doxycycline and synthetic penicillin).

Microscopic features:

Histologically, there is a superficial and deep perivascular and interstitial infiltrate of lymphocytes.

In some cases plasma cells and eosinophils are present. Eosinophils may be present at the site of tick bite. A few neutrophils may also be noted.

Special stain : Warthin-Starry silver stain - In some specimens  spirochetes are identified in the papillary dermis at the dermoepidermal junction.

Diagnosis may be confirmed by using an indirect immunofluorescence or immunoperoxidase techniques.

Borellia burgdorferi may also be identified in formalin-fixed paraffin-embedded lesions by polymerase chain reaction method. 

Visit:  Lyme Disease (Lyme Borreliosis) ; Acrodermatitis chronica atrophicans

                       

Further reading:

Multilocular erythema migrans in borreliosis.

Development of erythema migrans in spite of treatment with antibiotics after a tick bite.

Erythema migrans and serodiagnosis by enzyme immunoassay and immunoblot with three borrelia species

Epidemiological study of a cohort of adult patients with Erythema migrans registered in Slovenia in 1993.

The clinical spectrum of early Lyme borreliosis in patients with culture-confirmed erythema migrans.

Skin Pathology. D Weedon

April 2016

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)

 

 

Histopathology-India.net

Dermpath-India

Dermato pathology Cases

Pathopedia-India.com

Surgical-Pathology.com

Pathology-India.com

Pancreatic Pathology Online

Gallbladder Pathology Online

Paediatric Pathology Online

Paraganglioma-Online

Endocrine Pathology Online

Eye Pathology Online

Ear Pathology Online

Cardiac Path Online

Lung Tumour-Online

Mesothelioma-Online

Pulmonary Pathology Online

Nutritional Pathology Online

Environmental Pathology Online

Pathology Quiz Online

GI Path Online

Soft Tissue Pathology

Case Index

Infectious  Disease Online

E-book - History of  Medicine with special reference to India

Microscope Seeing the  Unseen.

 


 

Histopathology-India.net

 

Pathopedia-India.com

 

Surgical Pathology.com

 

Pathology-India.com

 

Dermpath-India

 

Gallbladder Pathology Online

 

Pathology Quiz Online 

 

Paediatric Pathology Online

 

Pancreatic Pathology Online

 

Paraganglioma-Online

 

Endocrine Pathology Online

 

Eye Pathology Online

 

Ear Pathology Online

 

Cardiac Path Online

 

Pulmonary Pathology Online

 

Lung Tumour Online

 

Mesothelioma-Online

 

Nutritional Pathology Online

 

Environmental Pathology Online

 

Soft Tissue Tumour Online

 

GI Path Online-India

 

Case Index

 

E-book - History of Medicine  

 

Microscope - Seeing the Unseen

 

 

 

Disclaimer

Privacy Policy  

Advertising Policy

Copyright 2016  histopathology-india.net