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Filoviruses are causative agents of a hemorrhagic fever in man with mortalities ranging from 22 to 88%.

Visit: Ebola Virus Disease ; Marburg Virus Disease

They are enveloped, nonsegmented negative-stranded RNA viruses and are separated into two types, Marburg and Ebola, which can be serologically, biochemically and genetically distinguished.

 The natural reservoir for filoviruses remains a mystery.

 Filoviruses are prime examples for emerging pathogens.

Factors that may be involved in emergence are international commerce and travel, limited experience in diagnosis and case management, import of nonhuman primates, and the potential of filoviruses for rapid evolution.

       

Ebola and Marburg viruses: the humans strike back.Med Sci (Paris). 2006 Apr;22(4):405-10

Characteristics of Filoviridae: Marburg and Ebola viruses.Naturwissenschaften. 1999 Jan;86(1):8-17

Emerging and reemerging of filoviruses.Arch Virol Suppl. 1996;11:77-100

 
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