Pathology of First Branchial Cleft Anomalies

Custom Search

Ear Pathology Online

Dr Sampurna Roy MD

First branchial cleft anomalies are rare and comprise 1%–8% of all branchial cleft anomalies.

They usually present in the first two decades of life.

Clinically, the lesion may present as cystic swelling, discharging fistulous opening or sinus.

Location - i) Usually noted in the pre-auricular or post-auricular region;

ii) cheek iii) upper part of the neck.

Gross: Branchial cleft cysts contain thin watery fluid, mucoid, or gelatinous material.

Microscopic feature: The lesions are lined by keratinized squamous epithelium. Foci of ciliated respiratory or pseudostratified columnar epithelium are also seen.

In Type I variety - there is absence of adnexa. In type 2 variety - there is adnexa along with cartilage.

Further reading:
Branchial anomalies in children.

Anomalies of the first branchial cleft - a review .

First Branchial Cleft Malformation with Duplication of external auditory meatus

First branchial cleft anomaly presenting as a recurrent post-auricular abscess.

First branchial cleft anomaly, a case for misdiagnosis.

First branchial cleft anomaly presenting as a recurrent post-auricular abscess.

First branchial cleft anomalies have relevance in otology and more.

First branchial cleft anomalies: a study of 39 cases and a review of the literature.