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Ear Pathology Online Pathology of First Branchial Cleft Anomalies
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First branchial
cleft anomalies are rare and comprise 1%–8% of all branchial cleft anomalies. They usually present in the first two decades of life. Clinically, the lesion may present as cystic swelling, discharging fistulous opening or sinus. Location - i) Usually noted in the pre-auricular or post-auricular region; ii) cheek iii) upper part of the neck. Gross: Branchial cleft cysts contain thin watery fluid, mucoid, or gelatinous material. Microscopic feature: The lesions are lined by keratinized squamous epithelium. Foci of ciliated respiratory or pseudostratified columnar epithelium are also seen. In Type I variety - there is absence of adnexa. In type 2 variety - there is adnexa along with cartilage.
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