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Pathology of First Branchial Cleft Anomalies

 Dr Sampurna Roy MD  

 

                                                                                                                      

 

 

First branchial cleft anomalies are rare and comprise 1%8% of all branchial cleft anomalies.

They usually present in the first two decades of life.

Clinically, the lesion may present as cystic swelling, discharging  fistulous opening or sinus.

Location - i) Usually noted in the pre-auricular or post-auricular region;   

ii) cheek iii) upper part of the neck.

Gross:  Branchial cleft cysts contain thin watery fluid, mucoid, or gelatinous material.

Microscopic feature:  The lesions are lined by keratinized squamous epithelium. Foci of ciliated respiratory or pseudostratified columnar epithelium are also seen. 

In Type I variety - there is absence of adnexa. In type 2 variety - there is adnexa along with cartilage.

 

Further reading:

Branchial anomalies in children.

Anomalies of the first branchial cleft - a review .

First Branchial Cleft Malformation with Duplication of external auditory meatus

First branchial cleft anomaly presenting as a recurrent post-auricular abscess.

First branchial cleft anomaly, a case for misdiagnosis.

First branchial cleft anomaly presenting as a recurrent post-auricular abscess.

First branchial cleft anomalies have relevance in otology and more.

First branchial cleft anomalies: a study of 39 cases and a review of the literature.

 

 

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)

 


 

 

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