 Site created by Dr Sampurna Roy MD
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Myxoid
Tumours of Soft Tissue Classification of Soft Tissue Tumour Gross examination of soft tissue specimen A practical approach to histopathological reporting of soft tissue tumours Grading of soft tissue tumours Fibroblastic/Myofibroblastic tumours |
Syn: Nasal Glioma ; Glial Heterotopias.
Nasal gliomas or heterotopia are nonhereditary congenital malformations composed of heterotopic neuroglial tissue.
Encephaloceles and
glial heterotopias are related tumour -like lesions. Encephaloceles are
usually associated with bony defects unlike glial heterotopias.
Site:
Occur in the subcutaneous tissue (60%) or may be intranasal in location
(30%).
Both external and intranasal components may be present.
Rarely may occur on the scalp, either as multiple subcutaneous nodules or as
a single midline parietal nodule.
Clinical
presentation:
The lesion
presents as reddish blue, firm nodule on the bridge of nose, usually at
birth or in early infancy.
Histopathology:
Image Link: click
Unencapsulated, multilobulated lesion composed of islands of neural and
fibrovascular tissue.
The neural tissue is composed of astrocytes set in a neurofibrillary stroma.
Neurons are usually absent.
Old cases show prominent stromal sclerosis.
Some cases show cystic change and rarely focal calcification.
Immunohistochemistry:
Glial
fibrillary acidic protein (GFAP), S-100 protein and
vimentin : Positive
The nodules do not contain meningeal covering (EMA is negative).
Complete surgical excision of nasal glial heterotopias is curative
| Abstracts:
Both nasal cerebral heterotopia and encephalocele in the same patient.Cleft Palate Craniofac J. 2006 Jan;43(1):112-6. Heterotopic neural nodules of the scalp.Plast Reconstr Surg. 2005 Feb;115(2):376-82. Nasal glial heterotopia: a clinicopathologic and immunophenotypic analysis of 10 cases with a review of the literature.Ann Diagn Pathol. 2003 Dec;7(6):354-9. Nasal glioma or nasal glial heterotopia? Morphological, immunohistochemical and ultrastructural study of two cases.Clin Neuropathol. 2002 ;21(2):66-71. Glial heterotopia in the subcutaneous tissue overlying T-12.J Cutan Pathol. 1999 Nov;26(10):523-7. Nasal glioma: an immunohistochemical and ultrastructural study.Pathol Int. 1995 May;45(5):393-8.
Congenital Cystic Adenomatoid Malformation
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Acute Respiratory Distress Syndrome
;Sarcoidosis
;Bronchiolitis
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Emphysema
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Bronchial Asthma
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Chronic Bronchitis
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Pulmonary
Alveolar Proteinosis
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Lipid Pneumonia ;
Pulmonary Hypertension
;Pulmonary edema
;Pulmonary Infection
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Pneumococcal Pneumonia
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Haemophilus influenza Infection;
Klebsiella Pneumoniae
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Mycoplasma Pneumonia
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Pneumocystis Pneumonia
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Legionellosis ;
Localized Fibrous Tumour of the Pleura
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Biphasic Epithelial/Mesenchymal Lung Tumours
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Pulmonary
Carcinosarcoma
;Pulmonary Blastoma
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Large Cell Neuroendocrine tumour;
Acrodermatitis chronica atrophicans
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Actinomycosis ;
Adenovirus ;
African Histoplasmosis
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AIDS: Cutaneous
lesion associated with AIDS ;
AIDS related malignant tumours
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African Trypanosomiasis
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Alphaviruses causing Encephalitis
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Amebic Meningoencephalitis
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American Trypanosomiasis
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Amoebiasis
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Arenavirus ;
Argentine hemorrhagic fever
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Arthropod-borne viral encephalitis
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Ascariasis ;
Aspergillosis ;Atypical Mycobacterial Infection
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| Normal Anatomy of the Nerve |
|
Reactive and hamartomatous lesions:
Fibrolipomatous hamartoma of nerve
Schwannoma (neurilemmoma)
Dermal nerve sheath myxoma
Malignant peripheral nerve sheath tumour Merkel cell (neuroendocrine) carcinoma Malignant primitive neuroectodermal tumour Miscellaneous neuroectodermal tumours presenting in soft tissue |
FUNCTIONAL ANATOMY OF THE HEARTANATOMY OF THE CORONARY ARTERIES AUTOPSY EXAM. OF CORONARY ARTERIES Myocardial infarctionhypertensive heart diseaseRHEUMATIC FEVER AND RHEUMATIC HEART DISEASEPATHOLOGY OF ASCHOFF BODIES OR NODULESmyocardiTISGIANT CELL MYOCARDITISpericardial diseaseHISTOPATHOLOGY REPORTING OF PERICARDIAL SPECIMEN HEART TRANSPLANTS - PATHOLOGICAL EXAMINATION ENDOMYOCARDIAL BIOPSY-(ALLOGRAFT REJECTION): ISHLT SYSTEM FOR GRADING REJECTION POST-OPERATIVE CARDIAC PATHOLOGY |