Malignant soft tissue tumours constitute a heterogeneous group of tumours with a wide range of biological behaviour. Histopathological grading is essential for separating tumours with favourable prognosis to those with poor prognosis and determines overall survival of the patient. Pathologists are required to indicate biological potential of the tumour, so that appropriate treatment regimen may be selected by the clinician. The criteria used in the grading scheme do not equally apply for all tumour types . Treating clinician should  be aware of  the limitations of the grading scheme, as there are frequent failures in the prediction of clinical outcome.

Note: Needle biopsies are not ideal for preoperative grading purposes.

 PARAMETERS USED IN GRADING:

Histological type
Necrosis
Mitotic activity
Cellularity
Tumour differentiation
Nuclear pleomorphism
Vascular invasion