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Metastatic Colonic Carcinoma in the Thyroid

Dr Sampurna Roy MD      




The thyroid harbours metastases, surprisingly, in 20% of patients dying of disseminated carcinoma.

Metastases, therefore, enter the differential diagnosis of all thyroid tumours.

In a case of metastatic colonic carcinoma to the thyroid the patient usually has a past medical history of colonic carcinoma and the histological and mucin histochemical features confirm the diagnosis. 

Renal cell carcinoma is a notorious and confusing source of intra-thyroid metastases. 

A review of the literature reveals that colon, melanoma, breast, renal , and lung carcinomas are the most frequent tumours to metastasize to the thyroid.

Metastatic disease must be considered in the differential diagnosis of cold nodules on radionuclide thyroid scans, particularly in patients with a known primary.


Further reading:

Colon carcinoma metastasis to the thyroid gland: report of a case with a review of the literature. 

Colon cancer metastatic to the lung and the thyroid gland.

Colonic carcinoma metastasis to the thyroid: a case of skip metastasis.

[Metastatic thyroid tumors from adenocarcinoma of the colon: clinical and anatomo-pathological contribution].

Thyroid metastases from colon cancer case report in a long term survivor.

Diagnosis of thyroid metastasis of colonic adenocarcinoma by fine needle aspiration biopsy.

Colon carcinoma metastatic to the thyroid gland.

Colon cancer metastasis to the thyroid gland.




Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)

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