| Colon carcinoma
metastasis to the thyroid gland: report of a case with a review of the
literature.Tumori.
2006 May-Jun;92(3):252-6.
Metastasis of colon cancer to the
thyroid gland is very rare and we would like to report a case we have
experienced, with a review of the literature. A 66-year-old woman
noticed a swelling in the anterior neck area and sought medical
attention at our department in August 2003. At age 63, she had
undergone surgery for cancer of the ascending colon, but subsequently
the cancer metastasized to the liver and she underwent an outer
hepatic segmentectomy. Fine-needle aspiration cytology indicated
adenocarcinoma with characteristic tall columnar cells, confirming our
suspicion that metastasis from the ascending colon cancer had already
occurred. Furthermore, lung metastasis was also suspected, because
several nodules were found in the lungs. On August 13, resection of
the left lobe of the thyroid gland and dissection of the cervical
lymph nodes were performed. Histopathology showed metastasis of the
ascending colon cancer to the thyroid and lymph nodes.
Colon cancer
metastatic to the lung and the thyroid gland.Arch
Surg. 2006 Jan;141(1):93-6.
The clinical
diagnosis of primary thyroid cancer is uncommon, constituting 1.5% of
all cancers in the United States. Clinically diagnosed metastatic
cancer to the thyroid gland is rare. Colon cancer is one of the most
common cancers in the United States, with a high propensity to
metastasize; 30% to 40% of patients have metastatic disease at the
initial diagnosis. The most common sites of metastasis from colon
cancer are the regional lymph nodes, the liver, the lung, and the
peritoneum. Colon cancer metastasis to the thyroid gland is rare, with
only a few reported cases, mainly in the pathology literature. These
cases describe metastasis from colon cancer to the thyroid gland that
became apparent years after the initial diagnosis of colon cancer and
were usually associated with dissemination to the liver, the lung, or
both. We report a case of colonic adenocarcinoma metastatic to the
thyroid gland and lung without involvement of the liver. A review of
the literature is also included.
Colonic carcinoma metastasis to the thyroid: a case of
skip metastasis.
J Laryngol Otol.
2005 Oct;119(10):834-6.
Colonic carcinoma
metastasis to the thyroid is rare. Here the authors present the case
of an 81-year-old lady who presented with metastatic colonic
adenocarcinoma in her thyroid gland. This case is unique as it is the
first to demonstrate metastasis from the colon to the thyroid with no
other site involvement. The use of cytokeratin immunohistochemical
staining is reviewed along with the current perspectives on the
concept of skip metastasis.
Metastatic thyroid tumors from adenocarcinoma of the
colon: clinical and anatomo-pathological contribution.
Tumori. 2003 Jul-Aug;89(4
Suppl):220-2.
We report herein
the case of a 43 year-old man who was operated 1998 of left colectomy
and hepatic resection for colic adenocarcinoma metastasized in the
liver. He suffers of multinodular goiter from some years; was admitted
to our hospital with a 2-month history of enlargement of goiter and
appearance of a new nodule. Physical and imaging examinations
disclosed a new nodules in the thyroid. Was operated of total
thyroidectomia and lymphoadenectomia cervical in the December 2002.
Histologic examinations revealed adenocarcinoma which was consistent
with a diagnosis of metastases from the primary colon adenocarcinoma
to the thyroid. The rarity, diagnosis, and prognosis of thyroid
metastasis from colon carcinoma are discussed.
Thyroid metastases from colon
cancer case report in a long term survivor.J Exp Clin Cancer Res. 2003 Dec;22(4 Suppl):243-5.
Colon cancer usually has an
hematogenous spread to liver and lung: rarely, or in the case of most
advanced disease, also brain and bone can be involved. Thyroid
metastasis is generally thought to be infrequent, breast and kidney
cancer being the most frequent causes. Herein we present the case of a
man affected by liver metastasis from colon cancer, who developed
unusual metastasis to thyroid.
Diagnosis of thyroid
metastasis of colonic adenocarcinoma by fine needle aspiration biopsy.
Acta Cytol. 1990 May-Jun;34(3):363-5.
A case of
thyroid metastasis from colonic adenocarcinoma was diagnosed by fine
needle aspiration (FNA) biopsy. The FNA specimen from the thyroid
nodule contained tall columnar cells consistent with the intestinal
primary. Staining of the tumor cells for thyroglobulin was negative.
Histologic examination of the excised nodule, which was removed due to
its rapid growth and risk of skin ulceration, confirmed the FNA
diagnosis. FNA biopsy in such cases should be able to distinguish
between a second primary neoplasm, which would be removed, and a
metastasis, which would usually not be surgically treated.
Colon carcinoma
metastatic to the thyroid gland.Clin
Nucl Med. 1986 Sep;11(9):634-5.
Metastatic
carcinoma to the thyroid gland rarely is encountered in clinical
practice; however, autopsy series have shown that it is not a rare
occurrence. A case of adenocarcinoma of the colon with metastases to
the thyroid is reported. A review of the literature reveals that
melanoma, breast, renal, and lung carcinomas are the most frequent
tumors to metastasize to the thyroid. Metastatic disease must be
considered in the differential diagnosis of cold nodules on
radionuclide thyroid scans, particularly in patients with a known
primary.
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